Why People Prefer Supplements Over Anti-Aging Drugs Like Metformin

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- Updated by Jody Mullis
Medically reviewed by Dr. Sidra Samad

  • People are more willing to take supplements than anti-aging drugs.
  • Exercise is the second most popular method, after supplements.
  • Metformin and rapamycin, although backed by science, are less favored.
  • Trust in medical institutions affects the willingness to take metformin.
  • Young participants show reluctance towards lifestyle interventions like fasting.
  • Cultural differences might influence the preferences for anti-aging strategies.

Why This Matters to Us: 

As longevity enthusiasts, understanding public preferences in anti-aging interventions helps us focus on what people are more likely to adopt. By identifying trends in willingness and skepticism, we can better communicate the benefits and address concerns about scientific methods aimed at extending healthy life spans. This study highlights the importance of trust and simplicity in public choices, guiding future educational efforts on longevity.

The Detail: 

A recent study published in Frontiers in Aging explored the public's willingness to incorporate various scientifically-backed anti-aging interventions into their lives. Participants, aged 18 to 85, with over 70% under 39, were surveyed on their readiness to engage in particular lifestyle changes aimed at promoting longevity.

The survey considered four main interventions: exercise, supplements, intermittent fasting, and anti-aging drugs like metformin and rapamycin. Results revealed a clear preference for taking supplements—such as omega-3 and NAD+ precursors—over other interventions. Supplements were deemed convenient and easy to integrate into daily routines, unlike the more demanding exercise regimen (combining aerobic and resistance training) or lifestyle methods like intermittent fasting.

Interestingly, while exercise was the second preferred option, followed by intermittent fasting, there was significant hesitancy about using drugs like metformin and rapamycin. These drugs are known for their potential to slow aging based on research, yet they remain less popular, mainly due to skepticism and a lack of widespread public understanding of their benefits. Trust in medical institutions was noted as a significant factor in whether participants would consider taking metformin, highlighting that even scientifically supported interventions need credibility and trust to be widely adopted.

This study also uncovered gender differences in preferences: males tended to favor exercise, while females showed more inclination towards supplements. The disparity between preference and action was notable, with a smaller portion actively engaging in any of the interventions.

One limitation of the study was its demographic: predominantly young and highly educated individuals from the Netherlands. This raises questions about how these findings might translate across different cultures and age groups, particularly since older adults might express different preferences due to their health concerns and chronic illness experiences.

In summary, the study draws attention to the challenges faced by emerging anti-aging sciences: overcoming skepticism and fostering broader acceptance. It suggests that as more evidence accumulates on the benefits of anti-aging drugs, public perception may shift, allowing these interventions to be embraced alongside simpler alternatives like supplements.