Introducing our ultimate stack to support optimal cognition:

• NR
• Fisetin
  
• Magnesium

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NMNH

NMNH is the next generation in NAD+ precursors, offering a revolutionary advancement in boosting NAD+ levels, with research demonstrating that it increases NAD+ levels up to 3x more effectively than traditional NMN. NAD+ is a vital coenzyme that drives numerous cellular processes, including energy production, DNA repair, and mitochondrial function. Here's how NMNH supports these critical functions in the body:

Enhanced NAD+ Synthesis: NMNH is rapidly converted into NAD+ within cells. By delivering this powerful precursor more efficiently than NMN, NMNH ensures a faster and higher surge in NAD+ levels, enabling robust cellular energy production and optimal metabolic function. NAD+ powers energy pathways such as glycolysis, the citric acid cycle, and oxidative phosphorylation, all of which are central to generating adenosine triphosphate (ATP)—the primary energy source of the body.

High-Efficiency ATP Generation: NMNH's ability to elevate NAD+ amplifies ATP production within the mitochondria. NAD+ drives oxidative phosphorylation, a process where electrons flow along the mitochondrial electron transport chain, pumping protons to create an electrochemical gradient. This gradient powers ATP synthase, allowing the production of ATP from ADP and inorganic phosphate, fueling every cellular function.

Mitochondrial Optimisation: Mitochondrial health is sustained and enhanced by NMNH-driven NAD+ levels. Mitochondria depend on sufficient pools of NAD+ for maintaining efficient energy production and cellular respiration. By supporting mitochondrial efficiency, NMNH helps prevent the decline in energy metabolism commonly associated with ageing and metabolic dysfunction.

DNA Repair Strengthened: NAD+ is essential for activating enzymes like PARPs (poly-ADP ribose polymerases), which repair DNA damage caused by environmental and internal stressors. NMNH’s superior NAD+ boosting ability enhances these repair processes, safeguarding the integrity of the genome and promoting cell survival.

Sirtuin Activation for Longevity: NMNH bolsters the activity of sirtuins, a family of NAD+-dependent enzymes involved in regulating metabolism, stress responses, and ageing. Elevated NAD+ levels help sirtuins modulate cellular processes related to longevity and resilience, contributing to improved energy balance and healthy ageing.

Potent Support for Redox Reactions: NAD+ is integral to cellular redox reactions, which involve the transfer of electrons that drive energy conversion and storage within cells. NMNH ensures a stable supply of NAD+ for these reactions, supporting efficient energy transfer and metabolic homeostasis.

Neuroprotection and Cellular Health: NMNH’s unprecedented capacity to enhance NAD+ levels also benefits brain health and longevity. By supporting energy production and combating oxidative stress, NMNH aids in protecting neurons from age-related decline while promoting overall cellular vitality.

In summary, NMNH represents a cutting-edge development in NAD+ supplementation. Its ability to drive NAD+ levels 3x higher than NMN translates to greater energy production, enhanced cellular repair, mitochondrial function, and overall health, making it a promising tool for healthy ageing and optimal cellular performance.

Fisetin: Fisetin is a powerful flavonoid found in various fruits and vegetables, particularly strawberries and apples, celebrated for its cognitive-enhancing properties. This remarkable compound boasts strong antioxidant and anti-inflammatory effects, which help protect brain cells from oxidative stress and inflammation, key factors in cognitive decline. Fisetin is known to stimulate neurogenesis, supporting the growth of new neurons and improving memory and learning capabilities. Additionally, it has been shown to enhance the expression of brain-derived neurotrophic factor (BDNF), a vital protein for brain health. Emerging research suggests that fisetin may help mitigate the effects of age-related cognitive decline, making it an essential addition to any cognitive enhancement regimen.

Magnesium: Magnesium is an essential mineral that plays a critical role in overall brain function and health. It is involved in over 300 enzymatic reactions in the body, including those that govern neurological functions. Magnesium helps maintain the health of neurons and is essential for the proper transmission of nerve impulses. As such, adequate levels of magnesium are necessary for memory, attention, mood, and stress management. It's known to regulate neurotransmitters, which send signals throughout the nervous system and brain, and also plays a role in protecting the brain against stress and neurotoxic factors.