Pure NR Sublingual Powder

 

  • Over 99% Pure Nicotinamide Riboside Powder
  • Independently lab tested
  • 100% Natural, Non-GMO
  • Gluten-Free, vegan and allergy friendly
  • Free 0.25ml scoop with every order
  • Free UK delivery on all orders
  •  


    lab certified

     

    Nicotinamide riboside is a potent longevity and anti-aging supplement that is known by a number of names. It is also known as NR, niagen, it is an alternative form of vitamin B3, which is also named niacin.


    Within your body, nicotinamide riboside is converted into NAD+, a helper molecule that exists inside each of your cells and supports many aspects of healthy aging.
    This is beneficial specifically because the amount of NAD+ in your body naturally falls with age and low NAD+ levels have been linked to health concerns like aging and chronic illnesses, such as diabetes, heart disease, Alzheimer’s disease and vision loss


    NR has been found to possess numerous potential health-related benefits including:

    • Improve mitochondrial function
    • Help protect brain cells
    • Support youthful cell-metabolism
    • Lower heart disease risk
    • Promote healthy muscle aging

     


    How Does NR Work?

    During the body's natural aging process, we often experience having less energy and vitality. This reduction has been linked to declining levels of NAD (nicotinamide adenine dinucleotide), a critical enzyme that is found in every cell in the body, which plays a role in helping to maintain healthy cell metabolism.



    One of the most important group of enzymes is the sirtuins, which have been shown to improve lifespan and overall health in animals. Studies indicate that sirtuins may repair damaged DNA, boost stress resistance, reduce inflammation and offer other benefits that promote healthy aging. These sirtuins are also known to be responsible for the lifespan-extending benefits of calorie restriction.


    Another group of enzymes are the Poly (ADP-Ribose) polymerases (PARPs), which have been shown to repair damaged DNA. Studies link higher PARP activity to reduced DNA damage and subsequently a longer lifespan.

    NR 3rd party lab report
    NR or NMN - which is better?

    More is known about NR and, consequently, it is more readily available with what appear to be good results. Its popularity as an anti-aging supplement would tend to support its potential efficacy. NMN is the ‘new kid on the block’ and is receiving very positive reviews as a health and wellness supplement.



    One of the main reasons why NMN is catching people’s attention is that where its chemical composition is concerned, it is nearer to NAD+ and therefore, presumably, more easily converted by the body into NAD+ than NR. Nicotinamide Riboside has to combine with a phosphate to convert it into NMN, before it can then become an effective precursor to NAD+. So, in answer to the question ‘Which is best?’, the answer isn’t yet known, but both, on the face of it, appear to be beneficial supplements in the anti-aging process.



    The alternative to taking either NR or NMN is cycling between the two of them
    Cycling supplements can be a smart move. With NR and NMN, the body produces a certain amount, depending on your age. However, there is the risk that if you introduce a higher-than-natural-level of these two precursors, the body’s metabolism may readjust and produce less of its own after a while, thus negating the benefits of a supplement. To counteract this problem, it is worth considering ‘cycling’ the two, by taking either NR for, say, a two-week period, then switching to NMN for a two-week period, then switching back to NR again, and so on…Another approach may be to alternate every day. Further studies are needed in this area.



    Recommended Daily Dosage:

    0.5 grams per day

     

    Upper Dosage:

    2 grams per day.



    Consideration:

    Like all vitamins, supplements and beneficial substances, it theorised that periodic breaks from NR (one to two days off) on a weekly basis. Further studies are needed on this and there is no firm evidence to suggest whether this practice is beneficial or not, but the theory is supported by a number of knowledgeable people in the field of human biology.



    Note:

    If you are on prescribed medication or have been medicating for a long term previously, then it is best to consult with your doctor before starting with NR.
    Keep the contents in the provided packaging or an airtight glass jar. Keep away from sunlight and avoid exposure to a temperature above 24 degrees Celsius. Keep in a cool dry place and don’t expose the contents to moisture. This product can be kept in a fridge or refrigerator.

     

    Our Packaging:

     

    Longevity Box NR powder is provided and supplied in re-sealable food-grade and food-safe pouches that are transparent on one side. NR does experience a degree of degradation over time. This degradation is still slow at room temperature but can be slowed further by storing it in the refrigerator. If you are planning to buy more than 3 months worth then it is recommended to store in the refrigerator.
    Scooping spoon are provided with every order that carries 125 mg of NR powder when leveled.
    Longevity Box also provides glass jars for storing your NR powder. These jars can contain approximately 50g the supplement, are re-sealable, and airtight. Ideal for people who have upped their dosage and need to take it on the go without having to deal with the hassle of using pouches.


    References and Further Readings:

     

    For the convenience of the customers and longevity enthusiasts, listed below are several links for references. Please keep in mind that none of the sources listed below are affiliated with LongevityBox in any way.



    https://pubmed.ncbi.nlm.nih.gov/26118927/
    Cantó C., Menzies K.J., Auwerx J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metab. 2015;22:31–53.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352172/#B1-nutrients-12-01616
    Mehmel M., Jovanovic N., Spitz U. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses. Nutrients. 2020;12:16

    https://pubmed.ncbi.nlm.nih.gov/29249689/
    Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. 2017 May 29

    https://www.cell.com/cell/fulltext/S0092-8674(07)00390-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS009286740700390X%3Fshowall%3Dtrue
    Belenky P, Racette FG, Bogan KL, McClure JM, Smith JS, Brenner C. 2007 May 4

     

     

     

    See Full Description

    lab certified

     

    Nicotinamide riboside is a potent longevity and anti-aging supplement that is known by a number of names. It is also known as NR, niagen, it is an alternative form of vitamin B3, which is also named niacin.


    Within your body, nicotinamide riboside is converted into NAD+, a helper molecule that exists inside each of your cells and supports many aspects of healthy aging.
    This is beneficial specifically because the amount of NAD+ in your body naturally falls with age and low NAD+ levels have been linked to health concerns like aging and chronic illnesses, such as diabetes, heart disease, Alzheimer’s disease and vision loss


    NR has been found to possess numerous potential health-related benefits including:

    • Improve mitochondrial function
    • Help protect brain cells
    • Support youthful cell-metabolism
    • Lower heart disease risk
    • Promote healthy muscle aging

     


    How Does NR Work?

    During the body's natural aging process, we often experience having less energy and vitality. This reduction has been linked to declining levels of NAD (nicotinamide adenine dinucleotide), a critical enzyme that is found in every cell in the body, which plays a role in helping to maintain healthy cell metabolism.



    One of the most important group of enzymes is the sirtuins, which have been shown to improve lifespan and overall health in animals. Studies indicate that sirtuins may repair damaged DNA, boost stress resistance, reduce inflammation and offer other benefits that promote healthy aging. These sirtuins are also known to be responsible for the lifespan-extending benefits of calorie restriction.


    Another group of enzymes are the Poly (ADP-Ribose) polymerases (PARPs), which have been shown to repair damaged DNA. Studies link higher PARP activity to reduced DNA damage and subsequently a longer lifespan.

    NR 3rd party lab report
    NR or NMN - which is better?

    More is known about NR and, consequently, it is more readily available with what appear to be good results. Its popularity as an anti-aging supplement would tend to support its potential efficacy. NMN is the ‘new kid on the block’ and is receiving very positive reviews as a health and wellness supplement.



    One of the main reasons why NMN is catching people’s attention is that where its chemical composition is concerned, it is nearer to NAD+ and therefore, presumably, more easily converted by the body into NAD+ than NR. Nicotinamide Riboside has to combine with a phosphate to convert it into NMN, before it can then become an effective precursor to NAD+. So, in answer to the question ‘Which is best?’, the answer isn’t yet known, but both, on the face of it, appear to be beneficial supplements in the anti-aging process.



    The alternative to taking either NR or NMN is cycling between the two of them
    Cycling supplements can be a smart move. With NR and NMN, the body produces a certain amount, depending on your age. However, there is the risk that if you introduce a higher-than-natural-level of these two precursors, the body’s metabolism may readjust and produce less of its own after a while, thus negating the benefits of a supplement. To counteract this problem, it is worth considering ‘cycling’ the two, by taking either NR for, say, a two-week period, then switching to NMN for a two-week period, then switching back to NR again, and so on…Another approach may be to alternate every day. Further studies are needed in this area.



    Recommended Daily Dosage:

    0.5 grams per day

     

    Upper Dosage:

    2 grams per day.



    Consideration:

    Like all vitamins, supplements and beneficial substances, it theorised that periodic breaks from NR (one to two days off) on a weekly basis. Further studies are needed on this and there is no firm evidence to suggest whether this practice is beneficial or not, but the theory is supported by a number of knowledgeable people in the field of human biology.



    Note:

    If you are on prescribed medication or have been medicating for a long term previously, then it is best to consult with your doctor before starting with NR.
    Keep the contents in the provided packaging or an airtight glass jar. Keep away from sunlight and avoid exposure to a temperature above 24 degrees Celsius. Keep in a cool dry place and don’t expose the contents to moisture. This product can be kept in a fridge or refrigerator.

     

    Our Packaging:

     

    Longevity Box NR powder is provided and supplied in re-sealable food-grade and food-safe pouches that are transparent on one side. NR does experience a degree of degradation over time. This degradation is still slow at room temperature but can be slowed further by storing it in the refrigerator. If you are planning to buy more than 3 months worth then it is recommended to store in the refrigerator.
    Scooping spoon are provided with every order that carries 125 mg of NR powder when leveled.
    Longevity Box also provides glass jars for storing your NR powder. These jars can contain approximately 50g the supplement, are re-sealable, and airtight. Ideal for people who have upped their dosage and need to take it on the go without having to deal with the hassle of using pouches.


    References and Further Readings:

     

    For the convenience of the customers and longevity enthusiasts, listed below are several links for references. Please keep in mind that none of the sources listed below are affiliated with LongevityBox in any way.



    https://pubmed.ncbi.nlm.nih.gov/26118927/
    Cantó C., Menzies K.J., Auwerx J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metab. 2015;22:31–53.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352172/#B1-nutrients-12-01616
    Mehmel M., Jovanovic N., Spitz U. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses. Nutrients. 2020;12:16

    https://pubmed.ncbi.nlm.nih.gov/29249689/
    Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. 2017 May 29

    https://www.cell.com/cell/fulltext/S0092-8674(07)00390-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS009286740700390X%3Fshowall%3Dtrue
    Belenky P, Racette FG, Bogan KL, McClure JM, Smith JS, Brenner C. 2007 May 4

     

     

     

    At LongevityBox we are committed to sourcing the highest purity longevity supplements on the market. Our products are pharmaceutical grade and independently verified for quality and purity by renowned third party test laboratories.

    We work with well established suppliers that have regular factory inspections and are certified with CGMP and ISO to ensure the highest standards are consistently met. We have third party independent laboratories test every batch of product that is produced and display on our website the latest tests for the batch that is currently in stock.

    -----

    Please see below the latest third party independent test certificates for our current batch of Longevity supplements.

    Independent laboratory testing is critical to ensure that the product is at least 99% pure and contains no dangerous levels of heavy metals or micro-organisms.If a retailer of is not providing test results then there is no certainty that there products is pure or even the product that they claim it to be and whether it’s safe for human consumption. Establishing purity and authenticity is critical when consuming small molecule Longevity supplements like NMN. It is clear that the market has many websites selling impure or fake NMN.

    Every batch of Longevity Box supplements is independently verified to have a purity of at least 99%, with no dangerous levels of heavy metals or micro-organisms. You can find the latest certifications for each product here:

    NMN purity certificates
    Resveratrol purity certificates
    NR purity certificates
    Ca-AKG purity certificates
    Spermidine purity certificates

    We are committed to your long term health and will always ensure our products are of the highest purity and quality.
     

     

    We want you to be delighted with every purchase from us. In the unfortunate and unlikely event that you’re not delighted we offer a 30-day Money Back Satisfaction Guarantee. 

    With our Money Back Satisfaction Guarantee we are committed to:

    - Issuing a full refund for all unopened products

    - Issuing a refund of 50% of the purchase price for returned products that have at least 50% of the product remaining for products up to the value of £300

     

    Return Procedures: Please send an email to CustomerServices@LongevityBox.co.uk with your complete name, address, phone # and your order # . Once we have received this email and confirmed that your order is eligible to be returned, we will provide you with a return authorisation number and a return address to send the goods.

     

    Once we have received your return package we will inspect for quality to ensure the product you return is genuine. This authenticity inspection may take up to 30 days. Upon confirmation of authenticity, you will receive your refund and email confirming that your return request has been accepted. You will either be credited back to your Card, or PayPal. Please allow 5 working days for us to process the refund and up to 5 working days to receive your refund by card.

     

    Unfortunately it is not possible for us to refund any delivery charges incurred when sending the product back to us.


    £24.99
    The UK's best prices guaranteed
    Free delivery with every order
    3rd party lab tested for purity
    -
    +
    We Shipping
    WorldWide
    100% Money Back
    Guarantee
    100% Secured
    Payment
    30-Day Return
    Policy