Insights from a Study on NMN's effectively as Anti-aging

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In a study published in the "Journal of Advanced Research" in March 2022, researchers conducted a comprehensive review on the effectiveness and safety concerns of nicotinamide mononucleotide (NMN) as an anti-aging product. The supplement has gained attention for its potential anti-aging properties, particularly concerning age-related diseases. The study can be found here.

The study highlighted the vital role nicotinamide adenine dinucleotide (NAD+) plays in our bodies. As we age, our NAD+ levels deplete, affecting various biological processes like energy production in mitochondria, DNA damage, cognitive impairment and inflammatory conditions. NMN comes into play here by boosting NAD+ levels in our body, thereby slowing the aging process.

Research investigations thus far have revealed some promising results. Multiple in vivo studies on animal models, including rats and mice, indicated that NMN supplementation could enhance NAD+ levels, improve insulin secretion, lipid profile and sensitivities, ameliorate eye dysfunction, help reverse age-related weight gain, and possibly extend life span. It also suggested possible positive impacts on age-related complications like diabetes, vascular dysfunction, cognitive impairments and susceptibility to acute kidney injury.

Results from these studies are positive, but one crucial piece is missing - a comprehensive investigation into the safety and efficacy of NMN administration in humans. Despite the growing influx of NMN-based anti-aging products on the market, there's still a lack of extensive human clinical trials. Given the crucial need for safety when dealing with anti-aging supplements, researchers in this study suggested further investigations are urgently needed.

In summary, NMN appears to be a promising potential addition to anti-aging health products. Still, more comprehensive investigations on effectiveness and safety are required before it can be confidently recommended.