How Olfactory Health Links to Cognitive Longevity and Ageing

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- Updated by Jody Mullis
Medically reviewed by Dr. Sidra Samad

  • The olfactory system plays a significant role in health and cognitive longevity.
  • Olfactory neurons can regenerate throughout life, unlike most brain neurons.
  • Loss of smell might be an early warning sign for neurodegenerative diseases.
  • Protecting olfactory health could reduce cognitive decline risks.
  • Alpha-lipoic acid (ALA) shows promise in restoring olfactory functions post-COVID-19.
  • Regular exercise aids in maintaining both physical and mental health.

 

 

 

 

Why This Matters to Us:

As longevity enthusiasts, this study is crucial because it underscores the important link between our sense of smell and long-term brain health. Understanding this connection broadens our toolkit for extending healthspan, potentially preventing or delaying cognitive decline.

The Detail:

Studies have shown that the olfactory system, responsible for our sense of smell, is vital for a healthy aging process. Unlike most neurons in the brain, which don’t regenerate easily, olfactory neurons can renew throughout our lives. This ability helps the olfactory system bounce back from damage due to infections, environmental toxins, or physical injuries. However, as we age, this regenerative power diminishes, which can lead to a loss of smell—a condition known as anosmia.

Anosmia is frequently linked to diseases like Alzheimer's and Parkinson's, showing that olfactory health is closely connected to cognitive longevity. For this reason, protecting smell abilities could be key to reducing cognitive decline as we age.

Dr. Andrew Huberman emphasizes the importance of maintaining olfactory health. He cites alpha-lipoic acid (ALA) as a potential intervention. ALA is an antioxidant that might protect neurons. In a personal example, Huberman restored his sense of smell lost to COVID-19 by using ALA. While promising, he cautions that more scientific research is needed to confirm ALA’s effectiveness as a long-term solution.

Moreover, regular physical exercise is indispensable for overall longevity. Staying active, whether through simple actions like walking or more intense workouts, is crucial not only for physical fitness but also for mental sharpness. Many older adults who remain intellectually proficient are those who stay physically active, highlighting the link between bodily movement and brain health.

In conclusion, this research emphasizes the significance of olfactory health in evaluating cognitive longevity. For further understanding, you can read the full study here.