Ultra Pure Methylene Blue

Toni C.

Verified Buyer

Excellent and definitely has a positive effect regarding tiredness, brain fog and inflammation 👍👍👍👍

See all reviews

Ultra Pure Methylene Blue

View latest third party test certificate

60 servings | 10mg dose | From £0.23 per serving

Precision methylene blue for cleaner energy, clearer focus, and steadier daily performance.

Energy: Enhance mitochondrial performance Brain: Boost focus and cognitive clarity Longevity: Protect cells from oxidative stress

With reverse osmosis distilled water

Third-party batch tested

700-day purity guarantee

Size 1 Bottle

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Save 23% £26.66 / Bottles

3 Bottles BEST VALUE 6 Bottles

Save 31% £23.99 / Bottles

6 Bottles

In stock • Ships today • 24–48 hour delivery

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60-day money back guarantee

Toni C.

Verified Buyer

Excellent and definitely has a positive effect regarding tiredness, brain fog and inflammation 👍👍👍👍

See all reviews

Zero Fillers or Binders

700-Day Purity Guarantee

Third-Party Batch Testing

Zero Fillers or Binders

700-Day Purity Guarantee

Third-Party Batch Testing

Join thousands who are extending their healthspan

Independently Verified Customer Reviews

“Really works at giving me more energy and focus.”

Mike W.

Verified Buyer

“Absolute visible pure compared to the other rubbish I bought elsewhere.”

Ian R.

Verified Buyer

“The dropper holds 15 drops which facilitates quick and easy application."

Patrick O.

Verified Buyer

“Fantastic company. I will keep ordering as long as they supply.”

Edel O’Callaghan

Verified Buyer

How to take it

The daily dose
Fifteen drops — 10mg of pharmaceutical-grade methylene blue — in a large glass of water, once a day, with or after food. One 60ml bottle is 60 doses, so a bottle lasts two months.

Drink it through a straw
Methylene blue is a dye. Sipped straight from the glass it will temporarily tint your teeth and tongue blue. Through a straw, it won't touch them. Rinse with plain water afterwards and you'll notice nothing at all. Any tint that does appear sits on the surface and brushes off — it doesn't stain enamel.

And yes, your urine will turn blue-green
Completely expected and completely harmless. It's the visible sign the dose has been absorbed and is clearing, and it settles within a day. Nobody warns first-time users about this, which is why it's the thing people email us about most.

When to take it
Morning or early afternoon suits most people. Some find it too energising close to bedtime — if that's you, move it earlier in the day rather than reducing the dose.

What it feels like
Steadier, not sharper. Most people describe cleaner energy through the afternoon rather than a stimulant hit. If you're expecting a rush, this isn't that, and it isn't meant to be.

What's in it
Two ingredients: USP pharmaceutical-grade methylene blue and reverse osmosis distilled water. No fillers, no flow agents, no cosmetic extras. What you're judging is the compound itself.

Actives Only
Backed by three guarantees

Zero fillers, zero binders, zero flow agents across the entire range.

Every order is covered three ways:

✓ THE PURITY CHALLENGE
Buy any Methylene Blue product with a cleaner label than ours, send us the receipt and label -we refund every penny you paid us.

✓ 60-DAY MONEY-BACK GUARANTEE
Not for you? Full refund, no questions.

✓ 700-DAY POTENCY GUARANTEE
Pure and potent from day 1 to day 700. Buy in bulk with confidence — your last bottle is guaranteed as strong as your first.

Actives Only

Backed by three guarantees

Zero fillers, zero binders, zero flow agents — across the entire range.
Every order is backed three ways:

✓ THE PURITY CHALLENGE: Buy any Methylene Blue product with a cleaner label than ours, send us the receipt and label — we refund every penny you paid us.

✓ 60-DAY MONEY-BACK GUARANTEE: Not for you? Full refund, no questions.

✓ 700-DAY POTENCY GUARANTEE: Pure and potent from day 1 to day 700. Buy in bulk with confidence — your last bottle is guaranteed as strong as your first.

Third-party Tested

Third-party Tested

Purity proof for every batch

Every batch is tested by an independent laboratory to verify what is in the product — and what is not.

Because purity claims mean nothing if they only come from the brand selling it.

View latest CoA →

Every batch is tested by an independent laboratory to verify what is in the product — and what is not.

Because purity claims mean nothing if they only come from the brand selling it.

View latest CoA →

What the evidence says

Why Methylene Blue Keeps Getting Studied

Low-dose methylene blue continues to attract research interest because it interacts with systems linked to cellular energy, brain function, and oxidative stress.

Studied for brain activity and memory performance

In a human study, low-dose methylene blue was associated with improved regional brain activity during memory tasks.

Why it matters: this helps explain why some users value it for cleaner focus and better mental endurance, rather than a stimulant-like spike.

Human evidence

Studied as a mitochondrial electron carrier

Mechanistic and review literature has explored its role in helping support mitochondrial respiration and oxygen use.

Why it matters: if a product supports the efficiency of cellular energy handling, the benefit may show up as steadier output and less drag across the day.

Mechanistic evidence

Studied for neuronal resilience and oxidative stress

Low-dose Methylene Blue has been studied in the context of neuronal resilience and reduced oxidative stress markers.

Why it matters: this is one reason the compound continues to attract interest in brain health and healthy ageing discussions.

Preclinical evidence

Low-dose Methylene Blue has been studied for brain activity and memory performance

In a human study, low-dose Methylene Blue was associated with improved regional brain activity during memory tasks.

Why it matters: this helps explain why some users value it for cleaner focus and better mental endurance, rather than a stimulant-like spike.

Human evidence

Methylene Blue has been studied as a mitochondrial electron carrier

Mechanistic and review literature has explored its role in helping support mitochondrial respiration and oxygen use.

Why it matters: if a product supports the efficiency of cellular energy handling, the benefit may show up as steadier output and less drag across the day.

Mechanistic evidence

Research has explored neuroprotective and oxidative-stress effectsJournal

Low-dose Methylene Blue has been studied in the context of neuronal resilience and reduced oxidative stress markers.

Why it matters: this is one reason the compound continues to attract interest in brain health and healthy ageing discussions.

Preclinical evidence

Measurable Results From Day 1

After 2 Weeks

Feel a noticeable boost in mental clarity and focus as the "backup wires" in your cellular power stations (mitochondria) begin to enhance energy flow.

After 6 Weeks

Experience a greater sense of resilience and steady energy as your metabolic sensors are fine-tuned, allowing your body to manage fuel and oxygen more efficiently.

After 12 Weeks

Notice a calmer, more balanced feeling across your systems as the inflammatory "static" between your cells is reduced, allowing for clearer and more harmonious communication.

After 6 Months

Benefit from sustained cellular protection as the long-term support for your DNA and cellular repair crews helps to reduce the accumulation of worn-out "zombie" cells.

After 2 Weeks

Feel a noticeable boost in mental clarity and focus as the "backup wires" in your cellular power stations (mitochondria) begin to enhance energy flow.

After 6 Weeks

Experience a greater sense of resilience and steady energy as your metabolic sensors are fine-tuned, allowing your body to manage fuel and oxygen more efficiently.

After 12 Weeks

Notice a calmer, more balanced feeling across your systems as the inflammatory "static" between your cells is reduced, allowing for clearer and more harmonious communication.

After 6 Months

Benefit from sustained cellular protection as the long-term support for your DNA and cellular repair crews helps to reduce the accumulation of worn-out "zombie" cells.

Proof vs. Promises

Longevity Box Methylene Blue

>99% Purity

Zero Nasties. Ever.

3rd Party Tested

700 Day Purity Guarantee

Evidence-Led Formulation

Other Brands

Inferior Purity

Fillers, Additives, Preservatives, Binders, Exipients

No Independent Testing

30 Day Guarantee

Rarely validated by top scientific institutions

You can buy methylene blue for £12. Here's what that buys.

We're not the cheapest and we're not going to pretend otherwise. Most cheap methylene blue is laboratory or industrial grade — manufactured to a standard that permits heavy metal residues and formaldehyde contamination, because it's intended for staining slides and treating fish tanks, not for daily human use. That standard is why it costs £12.

Ours is USP pharmaceutical grade, made with reverse osmosis distilled water, and independently tested batch by batch in a UK laboratory. The certificate for the batch you'll receive is on this page — not a link to a policy, the actual document, with the batch number and the purity figure on it.

And if you find a methylene blue with a cleaner label than ours, send us your receipt and the label. We'll refund every penny you paid us.

Targets 7 Hallmarks of Ageing

Mitochondrial Dysfunction

Supports the energy systems that help cells run cleanly and efficiently.

Deregulated Nutrient-Sensing

Supports broader discussions around energy efficiency and metabolic resilience.

Genomic Instability

Linked to antioxidant defence systems that matter for cellular stress protection.

Stem Cell Exhaustion

Relevant to the cellular conditions that help regenerative capacity hold up over time.

Cellular Senescence

Linked to antioxidant defence systems that matter for cellular stress protection.

Loss of Proteostasis

Relevant to autophagy and the internal housekeeping processes cells rely on over time.

Altered Intercellular Communication

Studied in relation to cellular stress signalling and inflammatory pathway balance.

Why we're this fussy

We started Longevity Box because we were buying longevity supplements we couldn't verify, from brands that wouldn't show us anything. Everything we sell, we take. Every batch is tested before it goes near a customer, and if a batch doesn't pass, it doesn't ship.

— Max & Caroline

Methylene Blue: Optimise Cellular Energy and Cognitive Function

Methylene Blue offers a unique and powerful approach to supporting cellular energy production and cognitive function. This well-studied compound enhances mitochondrial function and acts as a potent antioxidant, helping you unlock your cellular potential. Discover the benefits of Methylene Blue and take a step towards enhanced vitality and mental clarity.

Before you start:

Methylene blue is a monoamine oxidase inhibitor, and that matters for one group of people in particular. If you take an SSRI, SNRI, MAOI or tricyclic antidepressant — or any other serotonergic medication, including tramadol, triptans for migraine, or St John's Wort — do not take methylene blue without speaking to your doctor or pharmacist first. It is also not suitable if you have G6PD deficiency, if you are pregnant or breastfeeding, or if you...

Methylene Blue: Optimise Cellular Energy and Cognitive Function

Before you start:

Powering Cellular Energy:

Methylene Blue functions as an electron donor, aiding in the electron transport chain within mitochondria. This process promotes efficient cellular respiration and ATP production, resulting in increased energy levels and reduced fatigue.

Supporting Cognitive Health:

Methylene Blue has demonstrated neuroprotective properties in studies. It may help mitigate oxidative stress and support neuronal health, potentially enhancing memory, focus, and overall cognitive function.

Enhancing Mitochondrial Function:

As a mitochondrial enhancer, Methylene Blue supports the efficient operation of these cellular powerhouses. By optimising mitochondrial function, Methylene Blue helps your body produce more energy and operate at peak performance.

Methylene Blue: Designed for Optimal Effectiveness:

High Purity: Our Methylene Blue is synthesised and purified to ensure the highest quality and potency.
Optimal Absorption: Formulated for enhanced bioavailability, allowing you to experience the full benefits of Methylene Blue.
Precisely Dosed: Each serving provides a carefully measured dose of Methylene Blue for consistent and reliable results.
Convenient Formulation: Easy-to-use liquid or capsule form makes incorporating Methylene Blue into your daily routine simple and convenient.

Optimise your cellular energy and cognitive function with Methylene Blue, a compound that combines established science with cutting-edge innovation. Try it today and experience the difference!

Where methylene blue fits:

Methylene blue works at the electron transport chain — the point where fuel becomes usable energy. That makes it a complement to, not a substitute for, the other two levers most people pull for mitochondrial support.

Alongside NAD+ precursors. NAD+ support addresses the availability of the electron carrier. Methylene blue addresses what happens to those electrons downstream. Different points in the same pathway.

Alongside broader mitochondrial support. Where a formula like MitoSurge supports the machinery, methylene blue acts on the transport step itself.

On its own. Perfectly reasonable. It's a two-ingredient product with a clear mechanism — one of the few things in this category you can evaluate in isolation.

What we wouldn't do is stack it with three other things at once and start it all on the same day. If you want to know whether it's doing anything, change one variable.

Ingredients

Active Ingredients: Methylene Blue, reverse osmosis distilled water

All of our products are free from binders, fillers, preservatives, or additives. We pride ourselves on this as it’s truly unique to the supplement industry. We invite you to look at the ingredient labels from every other supplement brand and tell us if you find another brand with the same zero-tolerance policy across its entire range :)

How to use and store

Allergy Advice: Free from gluten, wheat, diary, eggs, soya and nuts.

Suggested dosage: Twenty (20) drops contain 10mg of pharmaceutical-grade methylene blue. Mix in a large glass of water, or as recommended by your healthcare practitioner. Store in a cool, dry air-tight and dark place to avoid degradation.

Warning: Dietary supplements should not be a substitute for a balanced diet and healthy lifestyle This product should be stored out of the reach of children. Do not exceed the stated recommended daily dosage.

Taste and practicality: It tastes of very little — faintly metallic in water, gone in a second. It will stain a worktop, a shirt or a wooden spoon if you spill it, so measure over the sink. And keep the cap on properly: the dropper is the...

Purity tests

Ensuring maximum levels of safety, purity and quality is everything to us. We work with well-established suppliers that have regular factory inspections and are certified with CGMP and ISO to ensure the highest standards are consistently met. Test House: Certified Laboratories

Delivery, Returns & Guarantee

60-Day Money Back Guarantee

Try it properly. Track how you feel. Keep what works.

Every Longevity Box product comes with a 60-day money back guarantee. If you don't notice a meaningful benefit within 60 days — or you simply change your mind — return it and we'll issue a full refund.

700-Day Purity Guarantee

Most brands promise purity at the point of manufacture. We guarantee it for the entire time you're using it.

Every Longevity Box product is covered by our 700-day purity guarantee — designed to ensure your supplements remain pure, reliable, and fit for purpose from the day they arrive to the day you finish them. That's the standard when you're playing the long game of healthspan.

Delivery

Fast fulfilment is part of product integrity. If you're building a...

Customer Reviews

Geraldine F.

Very happy! Delivery was quick and items arrived securely wrapped. Excellent customer service. So far enjoying using MB daily. Sleeping better and definitely noticed improvement in energy and focus. Will definitely order from the company again!

jason m.

Prompt delivery so far so good

Ruby H.

I am still experimenting with ut as the 10 an 5ml dosages are too much for me , so just yesterday I adjusted it for just few drops in my coffee and I think it works, will see how it will turn out.

Gary N.

Methylene Blue is an awesome addition to your health. It carries more oxygen around your body as it binds to the mitochondria. Your doctors will not share this with you either, nor will the pharmaceutical industry. Shame really as it is a power pack of nature for your body. As ever I can only write about my experience with this little gem. Also Longevity is a top notch retailer. I really cannot put into words how well my purchases have been handled. 10/10 for sure.

Thalia S.

Have been taking it for a week now. It’s very blue but otherwise I haven’t noticed anything.

Tracy B.

I ve only just received it, I will let you know when I ve used it.

Charles O.

Felt like it was watered down not as concentrated as other brands gona go bk to my old brand .

Simon V.

Great product and excellent service...highly recommended

Mindaugas S.

good purchase

Adam E.

Great

Simon V.

Great product and fantastic service...I will be a long time customer.

mike w.

Great stuff tastes a lot better than some others I have tried and really works at giving me more energy and focus I will be buying more if anyone else has any doubt about this stuff just try it and you will feel the difference

Ralph R.

Excellent I will order this again thank in the near future thank

Paul C.

My foggy brain is now clear and I’m sleeping much better

Marek R.

Doesn’t looks legal

Bobbie B.

Feeling alot more focused!

A S.

Not too sure on this product, seems very watered down. Can't feel any effect from it compared to another brand I was using previously. Difference is night and day

Janet W.

So far its been great in conjunction with red light therapy.. do your research.

Thomas I.

Loving so far. I take it most days, have a few off to cycle it. I’m also using it with my lotion on my skin .

Joe S.

Using 1ml with 1gm of NMN first thing in the mornng. Smooth physical and mental energy all day with no 4pm crash! Great products from a reliable company at a reasonable price! keep up the good work!

kevin s.

Actually the real deal :-)

Jen W.

Great product fast delivery.. would highly recommend..

Chris B.

Really works!

Louisa H.

The product arrived totally fine and as expected, I am just not a fan of the taste and it makes it hard for me to keep using it.

Barry B.

Quality

Carl C.

I held off writing a review until I’d been using for a couple of weeks. I have used methylene blue for around 2 years now and needed to switch to a UK supplier. I kid you not I did a lot of research. I am very happy I picked longevity box. I would recommend posting documentation on your website as proof on USP grade. As I hesitated in buying the product because this was not shown. But overall great product.

dorothy s.

I've not used it yet as I'm on taking the gummies

Ryan O.

Excellent company to deal with. Thank you

Davina l.

The taste is absolutely awful Can not stand to drink this unfortunately

Deepesh c.

Excellent at maintaining my energy levels when I have taken on a lot of activities

Anna T.

Thank you for being different

Sammy C.

Fantastic quality product and arrived quickly. I’m really glad I tried this, had a couple of days where I didn’t take it and saw an obvious drop in mood and focus. Thank you!

Richard P.

I've been using methylyne blue as a supplement for a few months, but never the liquid form, only capsules, as I didn't want the talked about 'blue mouth'. However, you don't get it with this supplier. You just add it to water and there isn't any residue left in your mouth or on your teeth. But actually I wouldn't even care about that anyway, as my reason for using it, was due to my previous research, in which it not only supports your mitochondria, but ipromotes mitochondria biogenesis. All I can tell you, is I'm currently consuming over 5,000 cals a day, as I'm trying to gain as much muscle as possible because I'm 50+, and since using methylyne blue, I've had to increase my calories significantly, due to my increased energy production as a result of mitochondrial enhancement.

David D.

Very fast delivery, after a week or so of taking I feel a considerable difference in my daily life , more clarity I'm not forgetting things as easily and feel my overall body health has greatly improved just from adding this to my daily routine,, a must have !!

Alison H.

Hubby swears by it

Alan G.

Only just started using, unsure of dosage. Have seen articles stating between 0.5mg to 10mg per day and the same as above but multiplied per kilo of body weight

James B.

Everything is as expected

R f.

Spot on

Paul C.

Early days but I’m feeling good and sleeping well

MR L.

Good price 1st of its kind I've tried

Jolanta R.

I like,use for one week

Diana B.

Very prompt, Thank you very much!

Gareth D.

One of the best, if not the best on the market

sam e.

Very good / quick delivery and service . MB definitely helps with brain clarity . I would order again .

Jon F.

Great but could be stronger

Patrick O.

A good quality product. The dropper holds 15 drops which facilitates quick and easy application i.e. no counting drops anymore. Delivery was fast and efficient with bottles well packed so all arrived in good condition. The bulk buy options also provides reasonable unit cost per bottle. I highly recommend the supplier for ease of ordering and quick and efficient delivery.

barry O.

It seems ok just trial and error at moment.

Cherie J.

Brought for my partner and he swears by it.

Vesselina S.

Amazing product.

Umair S.

As described

Karen M.

Feel great, so much more energy and much reduced anxiety

Frederick G.

Only just started it I’m on my 3rd dose and I can definitely feel a clearer head after dosing ⭐️⭐️⭐️⭐️⭐️

Laura M.

Amazing product. Will definitely order again

Betty S.

Waiting for results .

Nicholas K.

Worked well for long haul flight

Geoffrey M.

It’s 1st time using methalyne blue amazing focus and clarity

kamila K.

Working great, I feal fab

david m.

Seems ok

Michael H.

Works great

Andrew B.

Well packaged , clear smart presentation. Lets see if it works

ROBERT S.

i0[0[h0[h[

Anthony G.

Sensible bigger bottle, coloured glass to protect the contents. Dropper nice quality. The Methylene Blue itself appears to be good quality, crystal clear blue, mixes with water with no impurities or residue. Tasteless for the most part, there is a kind of very faint bitterness, hardly detectable. Be warned, before dilution this will stain, after dilution hardly at all. It's a 1% solution, probably as good as you are going to get anywhere. The key question is does Methylene Blue have health benefits? I was prepared to go on the strength of current information available. Best careful not to overdose and double check any possible interactions with prescription medication.

Catherine A.

Nothing to share

Paulo V.

Great service Good quality

Betty S.

Still experimenting with product!

David R.

I have Parkinson’s and looking to alleviate some stress it’s made a difference already, cognitive and focus is better than it was thank you

Mark G.

Quick delivery , great product , great price.

N D.

Just started using the Metholayne Blue and excited to feel the results :)

David J.

I love this product has gave me more energy and focus .

Matt H.

Pretty good for anxiety, does more for my cognitive health than some pharmaceuticals that cost like 5x the dose.

Brenda W.

I have been taking it for some time and it does seem to be helping my memory a little I think.

Ivaylo G.

All good. Thanks

Ronnie M.

Very happy with this product. I will definitely be ordering more. Thank you

Matthew T.

Amazing!

Tanya B.

Great quality thank you

Anjelika R.

It is the first time that I am taking methylene blue. It has been three weeks, I noticed slight improvement in the mental performance but no other changes. I have taken it just before getting flu and unfortunately it didn't make any difference.

Christian S.

Great service and product.

donna y.

Should not he for sake

Aga S.

Its difficult to say if the product itself is working as I just started taking it. I always wanted to try it so here We go

Michael l.

Amazing product, lives up to the hype

Emily-Rose S.

Pretty sure it does something. Fun thing to drink, too. Add it to apple juice - crazy colour! Taking a week off it, gonna start again and compare.

Ivaylo T.

It is fake

Mark M.

Definitely feel sharper taking MB

Brian S.

I’ve been using this product for a couple of weeks, I’m 115kg using 15 drops every other day, am I taking the right dose?

Tanya B.

Good quality and great service thanks

Samuel A.

Great customer service and timely delivery.

Yvonne M.

I’m very happy with my product. A great transaction, and prompt delivery with excellent communication. Thank you.

Carl N.

Service was great. Product was fine but honestly didn't see any difference positive or negative

Jenna C.

The taste is disgusting so I’ve not been able to tell if it works as I can’t bear the taste.

callum T.

Jonny B.

Great ultra pure product Top quality grade Quick and well packaged delivery Very competitively priced Highly recommended seller First class service

Dianne J.

Rudin X.

Sarah N.

Love this product - I'm all about Bio-Hacking and and having optimal health on a cellular level. The Methalyne Bluereally boosts my energy and leaves me rating to go! I combine it with Q10 & NAD+

Jackie C.

I ordered this for my Son who has many problems and I was sceptical… but the difference in him after 3 weeks is Mind blowing

stuart stephen j.

Love how its able to allow me to train my focus getting so much done.

Ian R.

Not happy with the new methelyne blue.the difference in the first lot i bought and this new batch is night and day. I thought I'd found my number one supplier fir this and now I've got to start looking somewhere else. Really not happy . I sent an email and its been ignored. I feel I'm a valued customer if yours buying many things but now I'm questioning my actions .WATCH THE VIDEO! And please don't try ro tell me the original one was too strong. I feel the difference between the 2

Cherie D.

Was brought for my partner so I can't comment on it but he likes using it.

Steve P.

This has helped with my anxiety no end. A great product

RICK L.

It has had zero affect, not noticed any difference. I have never drunk printer ink but I would imagine this is how it would taste. Having a blue tongue after drinking it is no great shake, drink it in the evening and by morning it has gone.

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