FAQ

What makes Magnesium Glycinate better than other forms of magnesium?

Most magnesium supplements use oxide or citrate forms because they're cheap to manufacture. The problem? Oxide has an absorption rate of around 4%. Glycinate is chelated — bonded to glycine — which dramatically increases intestinal absorption and reduces the laxative effect that plagues other forms. You're not just buying magnesium. You're buying magnesium that actually gets into your cells.

How quickly will I notice a difference?

Some people — particularly those with noticeable deficiency — feel calmer, sleep better, and experience less muscle cramping within one to two weeks. Full systemic benefits, including cardiovascular and metabolic improvements, typically consolidate after six to twelve weeks of consistent daily use.

Think of it as refilling a depleted reservoir. The speed of change depends on how depleted you were to begin with.

Will this interact with my medications?

Potentially — depending on what you're taking.

Magnesium can interact with the following drug categories:

• Antibiotics (fluoroquinolones and tetracyclines) — Magnesium can bind to these drugs and reduce their absorption. Space doses by at least two hours.
• Blood pressure medications — Magnesium has a mild blood pressure-lowering effect. If you're already on antihypertensives, monitor accordingly.
• Diabetes medications — Magnesium improves insulin sensitivity, which may enhance the effect of glucose-lowering drugs.
• Diuretics — Some increase urinary magnesium excretion; others reduce it. Clarify with your prescribing clinician.

Bottom line: If you're on prescription medication, run this past your GP (general practitioner) before starting. Not because this is dangerous — but because it works, and your doctor needs to know.

What is the correct dose?

Two capsules daily (1,500mg of Magnesium Glycinate) providing 150mg of elemental magnesium. This sits comfortably within evidence-based dosing ranges. Take with or without food — though evening dosing is preferred by many users due to the calming, sleep-supportive effect of both magnesium and glycine.

Are there any side effects?

Magnesium Glycinate is exceptionally well tolerated. Unlike magnesium oxide or citrate, it does not carry a significant laxative risk at standard doses. A very small minority of users may experience mild digestive softening in the first few days as the gut adjusts.

That's typically the full extent of it.

Who should avoid this supplement?

Individuals with chronic kidney disease (CKD) should not take magnesium supplements without medical supervision, as impaired kidneys cannot excrete excess magnesium efficiently. If you are pregnant, nursing, or managing a serious medical condition, consult your healthcare provider before use.

Is magnesium deficiency actually common?

More common than most people realise. Soil depletion, food processing, alcohol consumption, and chronic stress all deplete magnesium. Studies estimate that a significant proportion of adults in Western countries fail to meet even the basic RDA (recommended daily allowance) — let alone the optimal intake required for high-performance ageing.

If you sleep poorly, cramp, feel anxious, or fatigue easily, low magnesium status is a credible and frequently overlooked contributor.

Can I take this alongside other Longevity Box supplements?

Yes. Magnesium Glycinate is a foundational supplement and complements virtually the entire Longevity Box range. It is particularly synergistic with Vitamin D3 + K2 (magnesium is required to activate and transport vitamin D), NMN or NMNH (magnesium is essential for NAD+ metabolism), and any sleep or stress support protocol.

What should I do if I miss a dose?

Take it as soon as you remember, unless it is close to your next scheduled dose. Do not double up. Missing a day or two will not reverse progress — magnesium repletion is a gradual, cumulative process, not one that resets overnight.