Over 99% pure
Independently lab tested
Gluten-free, vegan and allergy friendly
1,000mg Ca-AKG per serving
30 day supply

What is Ca-AKG and How Does it Work?

AKG is known to rejuvenate cellular energy and promote cell renewal, aiding in the prevention of age-related issues and frailty. As we age, AKG production declines dramatically, with levels at age 80 dropping to just 10% of those at 40. Taking calcium AKG (Calcium Alpha-Ketoglutarate) supplements can enhance both lifespan and healthspan, helping you maintain health as you age. This powerful calcium salt comprises pure calcium combined with alpha-ketoglutarate, a key player in cellular energy metabolism and the Krebs cycle. Calcium AKG supports the process that creates ATP, which is essential for converting food into usable cellular energy. This essential supplement balances calcium's supportive role in bone health with AKG's power to facilitate cellular energy production, making it a powerhouse for promoting longevity and metabolic function [1].

The Role of Calcium AKG in Energy Production

Calcium AKG is deeply involved in the energy production process that fuels the body's cellular activities. The role of AKG in the citric acid cycle is foundational, as it contributes to the efficient transformation of nutrients into energy within the mitochondria. This action promotes cellular energy balance, helping to support cellular and metabolic functions that are crucial for maintaining robust health throughout the ageing process. By bolstering energy metabolism, Ca-AKG helps counteract the energy decline that often accompanies ageing [3].

How Ca AKG Supports Longevity and Lifespan

Interest in Ca-AKG has grown significantly as research suggests that it may help to increase both lifespan and healthspan. By aiding cellular processes, Ca-AKG can promote longevity by enhancing cellular functions that typically decrease with age, such as autophagy, known as the process that clears dysfunctional cells. Ca-AKG may also positively influence DNA methylation and protein synthesis, important markers of biological age. These actions make Ca-AKG a key supplement for those seeking to decode age and promote a healthier, longer life [4][5].

Exploring the Benefits of Calcium Alpha-ketoglutarate for Bone Health

Beyond its role in energy production, Ca-AKG is a potent ally in promoting bone health and muscle strength. The inclusion of calcium in Ca-AKG supports optimal bone density and structural integrity, which are vital as we age and our bones naturally weaken. This supplement can help support bone formation and maintenance while also contributing to improved collagen production, which is necessary for maintaining flexible, strong bones. Taking calcium AKG assists in preventing bone loss and promotes overall bone and muscle health [6].

Why Choose Ca-AKG Capsules for Healthy Ageing?

Ca-AKG capsules are a convenient and highly effective supplement form that ensures consistent daily intake. The capsules contain a precise dosage of Ca-AKG, simplifying the routine of supporting your metabolic functions and cellular energy. This ease of use makes Ca-AKG capsules a practical choice for those looking to enhance their longevity and health span continuously. The capsule form allows for better absorption of pure calcium alpha-ketoglutarate, maximizing its benefits [7].

Can Ca-AKG Improve Biological Age and Muscle Strength?

Ca-AKG offers an innovative way to address biological age markers by supporting processes like protein synthesis and autophagy. This supplement's dual action on cellular energy and bone health can help maintain muscle strength and vitality over time. It plays a role in energy production within cells and supports bone and muscle health, helping to maintain the structural integrity and functional capacity of your body as it ages. This truly makes Ca-AKG an extensive supplement supporting long-term health and vitality [8].

What Are Customer Reviews Saying About Ca-AKG?

Customers consistently report positive experiences with Ca-AKG, citing notable improvements in energy levels, vitality, and overall health. Many have experienced enhanced bone strength and a stronger sense of well-being since starting the supplement. The effectiveness of Ca-AKG in reducing signs of ageing and promoting overall energy has resonated with users seeking a safe, reliable way to support their longevity.

Is Ca-AKG Right for Your Metabolic Health?

Ca-AKG is a remarkable supplement that supports various metabolic functions necessary for sustaining health as we age. It provides essential amino acids like glutamine and glutamate, which are critical for metabolic processes. By aiding in the regulation of blood sugar levels and reducing chronic inflammation, Ca-AKG helps ensure your metabolic system operates effectively. The supplement supports maintaining energy levels and metabolic efficiency, which contribute to optimal health conditions [9].

Why Choose Our Ca-AKG Supplement?

Selecting the right supplement means choosing one that prioritises quality ingredients and rigorous quality control and third party testing. Every batch of our Ca-AKG supplement is independently tested for safety and efficacy, ensuring each dose is reliable. By using the finest source ingredients and developed in an FDA CGMP facility, we guarantee an exceptional quality spermidine product that meets the highest standards.

Our Ca-AKG is also free of additives, fillers, binders or preservatives. You will find nothing but active ingredients in every single Longevity Box supplement.

Our world-leading 700-day purity guarantee

Our 700-day purity guarantee ensures that our products remain pure and reliable form the moment they arrive until you finish taking them. Peace of mind that you truly are extending your healthspan.

References

Krebs HA, Johnson WA. "The Role of Citric Acid in Intermediate Metabolism in Animal Tissues." Enzymologia. 1937.
Chin RM, et al. "The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR." Nature. 2014.
Pawlowska E, et al. "Mitochondrial function and ageing: Do mitochondria play a role in the age-related decline of cellular metabolism?" Mitochondrion. 2013.
Zhang J, et al. "The metabolic regulator α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR." Cell Reports. 2020.
Lu H, et al. "α-Ketoglutarate orchestrates cellular programaes to regulate DNA methylation." Nature Communications. 2020.
Uebelhart D, et al. "Effects of oral calcium supplements on femoral bone mineral density in elderly osteoporotic patients." Bone. 1993.
Gertz M, et al. "Assessment of bioavailability of different calcium salts using serum calcium response curve methodology" Journal of Clinical & Integrative Medicine. 2014.
Wu Y, et al. "Calcium alpha-ketoglutarate enhances protein synthesis and protects against muscle wasting" European Journal of Nutrition. 2016.
Sun K, et al. "The phosphoenolpyruvate-Krebs cycle shuttle and aging: Mechanisms of neuroprotection and cardioprotection." Experimental Gerontology. 2016.
Baziuk N, et al. "Quality Assurance in Nutritional Supplement Production." Comptes Rendus Chimie. 2016.

Pure Calcium Alpha-Ketoglutarate - CA-AKG Supplement