Bulk Buy - Pure Apigenin Powder

Get the UK's and Europe's best prices by buying in bulk! 

 

  • Over 99% pure Apigenin powder
  • Independently lab tested
  • 100% Natural, Non-GMO
  • Gluten-Free, vegan and allergy-friendly
  • Free 0.25ml scoop with every order
  • Free UK delivery on all orders

lab certified

Apigenin has been found to possess numerous potential health-related benefits including:

  • Supports prostate health
  • Promotes glucose metabolism
  • Maintains nervous system function
  • Supports skin health
  • Anti-inflammatory abilities 



What Is Apigenin

 

Apigenin is a compound found in a wide variety of herbs, fruits and vegetables.  It is a naturally occurring flavonoid that inhibits CD38, and crucially, in turn boosts NAD+ levels. It is a particularly interesting substance for health and longevity researchers, with extensive studies that have focused on its anti-inflammatory, antioxidant, anti-stress, pro-mitochondrial, antineoplastic, neuroprotective, and broad adaptogenic effects. Androgenic effects have also been found, assisting the body in the production of protective androgens that keep estrogen, cortisol, and various stress chemicals in check.




How Does It Work?

The observed reduction in inflammation is understood to be due to its ability to suppress the release of numerous inflammatory mediators including inducible nitric oxide synthase (iNOS), nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), Th1 cytokines interferon-gamma (IFN-γ), and interleukin-2 (IL-2).

Upon consumption of Apigenin, it is rapidly metabolized and released into the serum as glucuroside and sulfate conjugates. With a half-life of 92 hours, Apigenin is present in the blood up to 24 hours after initial ingestion. The anti-inflammatory effects of Apigenin are via the suppression of NO-synthase induction and COX2 enzymes in macrophages. There are also inhibitory effects on Interleukin-4 production. Apigenin has also been shown to potentially suppress TNFa elevations and potentially TNFa induced upregulation of adhesion molecules.




Experts view:

Dr Brad Stanfield talks about Apigenin and it's beneficial properties.



 

 

Dosage and Guidance

Take with or without food. Can be mixed in a meal or drink. Due to 

 

Suggested Daily Dosage:

0.25 grams per day.

Upper Dosage (Depending upon the age and other factors):

1 grams per day.





Referencing and Further Readings:

For the individuals who are interested in more details and knowledge about Apigenin, here is a list of references to help you with your study. Moreover, you can watch this video by Dr Eric Berg where he provides an overview of the benefits of Apigenin

 

Salehi B., Venditti A., Sharifi-Rad M., Kręgiel D., Sharifi-Rad J., Durazzo A., Lucarini M., Santini A., Souto E.B., Novellino E., et al. Int. J. Mol. Sci. 2019.20.13


    Wang M., Firrman J., Liu L., Yam K. BioMed Res. Int. 2019;2019

     

     Ali, F. Rahul, F. Naz, S. Jyoti, and Y. H.Siddique. 2017; International Journal of Food Properties

     

       Zhou, Yulin; Wang, Zhenzuo; Xu, Lixin; Tang, Haifeng; Wang, Di; et al. Journal of Investigative Medicine, Dec 2016

       

      Disclaimers:

      • It is advised to use this product at your own discretion. 
      • Our products are supplements and should not be considered as an alternative for a varied diet.
      • Consult with your doctor before incorporating it into your daily routine.
      • Research on Apigenin is still ongoing and as more is discovered, the content on this website may get updated or changed altogether.

       

      See Full Description

      lab certified

      Apigenin has been found to possess numerous potential health-related benefits including:

      • Supports prostate health
      • Promotes glucose metabolism
      • Maintains nervous system function
      • Supports skin health
      • Anti-inflammatory abilities 



      What Is Apigenin

       

      Apigenin is a compound found in a wide variety of herbs, fruits and vegetables.  It is a naturally occurring flavonoid that inhibits CD38, and crucially, in turn boosts NAD+ levels. It is a particularly interesting substance for health and longevity researchers, with extensive studies that have focused on its anti-inflammatory, antioxidant, anti-stress, pro-mitochondrial, antineoplastic, neuroprotective, and broad adaptogenic effects. Androgenic effects have also been found, assisting the body in the production of protective androgens that keep estrogen, cortisol, and various stress chemicals in check.




      How Does It Work?

      The observed reduction in inflammation is understood to be due to its ability to suppress the release of numerous inflammatory mediators including inducible nitric oxide synthase (iNOS), nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), Th1 cytokines interferon-gamma (IFN-γ), and interleukin-2 (IL-2).

      Upon consumption of Apigenin, it is rapidly metabolized and released into the serum as glucuroside and sulfate conjugates. With a half-life of 92 hours, Apigenin is present in the blood up to 24 hours after initial ingestion. The anti-inflammatory effects of Apigenin are via the suppression of NO-synthase induction and COX2 enzymes in macrophages. There are also inhibitory effects on Interleukin-4 production. Apigenin has also been shown to potentially suppress TNFa elevations and potentially TNFa induced upregulation of adhesion molecules.




      Experts view:

      Dr Brad Stanfield talks about Apigenin and it's beneficial properties.



       

       

      Dosage and Guidance

      Take with or without food. Can be mixed in a meal or drink. Due to 

       

      Suggested Daily Dosage:

      0.25 grams per day.

      Upper Dosage (Depending upon the age and other factors):

      1 grams per day.





      Referencing and Further Readings:

      For the individuals who are interested in more details and knowledge about Apigenin, here is a list of references to help you with your study. Moreover, you can watch this video by Dr Eric Berg where he provides an overview of the benefits of Apigenin

       

      Salehi B., Venditti A., Sharifi-Rad M., Kręgiel D., Sharifi-Rad J., Durazzo A., Lucarini M., Santini A., Souto E.B., Novellino E., et al. Int. J. Mol. Sci. 2019.20.13


        Wang M., Firrman J., Liu L., Yam K. BioMed Res. Int. 2019;2019

         

         Ali, F. Rahul, F. Naz, S. Jyoti, and Y. H.Siddique. 2017; International Journal of Food Properties

         

           Zhou, Yulin; Wang, Zhenzuo; Xu, Lixin; Tang, Haifeng; Wang, Di; et al. Journal of Investigative Medicine, Dec 2016

           

          Disclaimers:

          • It is advised to use this product at your own discretion. 
          • Our products are supplements and should not be considered as an alternative for a varied diet.
          • Consult with your doctor before incorporating it into your daily routine.
          • Research on Apigenin is still ongoing and as more is discovered, the content on this website may get updated or changed altogether.

           

          At LongevityBox we are committed to sourcing the highest purity longevity supplements on the market. Our products are pharmaceutical grade and independently verified for quality and purity by renowned third party test laboratories.

          We work with well established suppliers that have regular factory inspections and are certified with CGMP and ISO to ensure the highest standards are consistently met. We have third party independent laboratories test every batch of product that is produced and display on our website the latest tests for the batch that is currently in stock.

          -----

          Please see below the latest third party independent test certificates for our current batch of Longevity supplements.

          Independent laboratory testing is critical to ensure that the product is at least 99% pure and contains no dangerous levels of heavy metals or micro-organisms.If a retailer of is not providing test results then there is no certainty that there products is pure or even the product that they claim it to be and whether it’s safe for human consumption. Establishing purity and authenticity is critical when consuming small molecule Longevity supplements like NMN. It is clear that the market has many websites selling impure or fake NMN.

          Every batch of Longevity Box supplements is independently verified to have a purity of at least 99%, with no dangerous levels of heavy metals or micro-organisms. You can find the latest certifications for each product here:

          NMN purity certificates
          Resveratrol purity certificates
          NR purity certificates
          Ca-AKG purity certificates
          Spermidine purity certificates

          We are committed to your long term health and will always ensure our products are of the highest purity and quality.
           

           

          We want you to be delighted with every purchase from us. In the unfortunate and unlikely event that you’re not delighted we offer a 30-day Money Back Satisfaction Guarantee. 

          With our Money Back Satisfaction Guarantee we are committed to:

          - Issuing a full refund for all unopened products

          - Issuing a refund of 50% of the purchase price for returned products that have at least 50% of the product remaining for products up to the value of £300

           

          Return Procedures: Please send an email to CustomerServices@LongevityBox.co.uk with your complete name, address, phone # and your order # . Once we have received this email and confirmed that your order is eligible to be returned, we will provide you with a return authorisation number and a return address to send the goods.

           

          Once we have received your return package we will inspect for quality to ensure the product you return is genuine. This authenticity inspection may take up to 30 days. Upon confirmation of authenticity, you will receive your refund and email confirming that your return request has been accepted. You will either be credited back to your Card, or PayPal. Please allow 5 working days for us to process the refund and up to 5 working days to receive your refund by card.

           

          Unfortunately it is not possible for us to refund any delivery charges incurred when sending the product back to us.


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