{"title":"Targeted Actives","description":"\u003cp\u003e\u003cspan\u003eSingle-molecule precision. High-purity actives for your stack.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"pure-resveratrol-supplement","title":"Pure Trans Resveratrol Supplement Capsules","description":"\u003cul\u003e\n\u003cli\u003eOver 99% pure\u003c\/li\u003e\n\u003cli\u003eIndependently lab tested\u003c\/li\u003e\n\u003cli\u003eNo additives, binders or fillers\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003eGluten-free, vegan and allergy friendly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c!-- new tab --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- tab content --\u003e\n\u003cdiv style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"lab certified Resveratrol UK\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eAbout Our Resveratrol Supplements:\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eResveratrol is a naturally occurring compound and is a polyphenol which is present in a number of common food items such as berries, grapes, vine, peanuts, etc. Plants that produce resveratrol do so partly as a protective mechanism and response to stressors within their environments, including the presence of insects or other predators, damage, injury, and fungal varieties. Resveratrol is believed to be one of the most potent polyphenols.\u003c\/p\u003e\n\u003cp\u003eThe properties of resveratrol were first discovered when researchers established that a variety of yeasts, microbes, insects and animals that were fed resveratrol experienced an increased lifespan. Several studies continued to confirm these properties in their successful work on flies, fish, mice and nematode worms, all of which lived longer compared to control groups that were not treated with this phytonutrients.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch2\u003e\u003cstrong\u003eHow Does Resveratrol Supplement Work?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eResveratrol supplements can either passively cross cell membranes or interact with its receptors due to its unique physical and chemical properties, making it possible for Resveratrol to interact with inter and extracellular molecules effortlessly. It is because of this that its mechanism of action is triggered by one of the two means (at a cellular level):\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBy developing its effect inside the nucleus\u003c\/li\u003e\n\u003cli\u003eActivating intracellular mechanism by first activating signalled pathways when binding to receptors of the cell membrane\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe way it potentially functions as a longevity-promoting substance can possibly be explained by how it activates SIRT. A study suggests that it can directly activate the NMNAT enzyme, which increases the intracellular activity and levels of NAD+, which is likely to affect SIRT, which primarily requires the presence of NAD+ in order to function. In another experiment, human cells were treated with Resveratrol independent of NMNAT enzyme. Even without the presence of NMNAT, Resveratrol still rejuvenated old cells, which started to divide and develop longer telomeres with the restoration of the splicing factor expression. The cells not only started to appear younger but behaved more like younger cells as well.\u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003e\u003c\/h2\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eBenefits of Resveratrol\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe benefits of resveratrol are robust, thanks to its potential roles as a longevity agent and heart health supporter. It is thought to improve blood flow and reduce cholesterol levels, contributing to cardiovascular advantages. Resveratrol's anti-inflammatory properties can also help manage chronic inflammation, further emphasising its potential as part of a comprehensive wellness regime.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eAdditionally, resveratrol is being explored as a compound that supports brain health, with some studies suggesting it could offer protective benefits against cognitive decline.\u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003e\u003c\/h2\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eHow Much Resveratrol Should You Take?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eUnderstanding the correct dosage of our resveratrol supplement is essential for maximising its benefits while minimising any potential side effects. The suggested daily serving ranges from 500 mg, to 1,000 mg.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e\u003cspan\u003eMultiple studies have observed that Resveratrol’s bioavailability can be improved when consumed with a food that has an element of fat content. This observation is in alignment with Professor David Sinclair’s approach, which is to take Resveratrol with yoghurt at breakfast. \u003c\/span\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25347459\/\" rel=\"noopener\" title=\"Enhancing the delivery of resveratrol in humans\" target=\"_blank\"\u003eThis paper\u003c\/a\u003e\u003cspan\u003e explores the various studies on intake options. Other studies, also included in the aforementioned paper, have indicated that taking Resveratrol with green tea will enhance its effects and that it is best taken on an empty stomach.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eDoes Resveratrol Fit Into a Vegan Diet?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFor those following a vegan diet, trans resveratrol supplements offer a plant-based option to bolster nutritional intake without animal-derived ingredients. Our trans-resveratrol come in vegan-friendly capsules, using cellulose for the capsule shell instead of gelatin, and are free from animal products.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThis supplement can effectively complement other vegan supplements like magnesium, vitamin B12, or vitamin D to provide comprehensive dietary support.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eResveratrol in the UK: Where to Find and What to Expect?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eResveratrol supplements are widely available in the UK, both online and in health food stores. Consumers should seek products where each batch is independently tested for quality and purity, ensuring they are free from unnecessary additives or fillers.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eReading customer reviews can provide insights into the effectiveness and quality of specific products, helping buyers make informed choices.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eReferences and Further Readings:\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3 class=\"heading-title\"\u003eSmall molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12939617\/\" rel=\"noopener\" title=\"Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.\u003c\/a\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12939617\/\" rel=\"noopener\" title=\"Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan\" target=\"_blank\"\u003enlm\u003c\/a\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12939617\/\" rel=\"noopener\" title=\"Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan\" target=\"_blank\"\u003e.nih.gov\/12939617\/\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHowitz, K.T., Bitterman, K.J., Cohen, H.Y., Lamming, D.W., Lavu, S., Wood, J.G., Zipkin, R.E., Chung, P., Kisielewski, A., Zhang, L.L. and Scherer, B., 2003. \u003cem\u003eNature\u003c\/em\u003e, \u003cem\u003e425\u003c\/em\u003e(6954), pp.191-196.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3 id=\"page-title\" class=\"highwire-cite-title\"\u003eConcentration of the Phytoalexin Resveratrol in Wine\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ajevonline.org\/content\/43\/1\/49\" rel=\"noopener\" title=\"Concentration of the Phytoalexin Resveratrol in Wine\" target=\"_blank\"\u003ehttps:\/\/www.ajevonline.org\/content\/43\/1\/49\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSiemann, E.H. and Creasy, L.L., 1992.  \u003cem\u003eAmerican Journal of Enology and Viticulture\u003c\/em\u003e, \u003cem\u003e43\u003c\/em\u003e(1), pp.49-52.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003eDevelopment of a lozenge for oral transmucosal delivery of trans-resveratrol in humans\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0090131\"\u003ehttps:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0090131\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eBlanchard, O.L., Friesenhahn, G., Javors, M.A. and Smoliga, J.M., 2014. \u003cem\u003ePloS one\u003c\/em\u003e, \u003cem\u003e9\u003c\/em\u003e(2), p.e90131.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003ch3\u003eCaloric restriction mimetics slow aging of neuromuscular synapses and muscle fibers\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4963347\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4963347\/\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eStockinger, J., Maxwell, N., Shapiro, D., deCabo, R. and Valdez, G., 2018. \u003cem\u003eThe Journals of Gerontology: Series A\u003c\/em\u003e, \u003cem\u003e73\u003c\/em\u003e(1), pp.21-28.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003eCalorie restriction-like effects of 30 days of resveratrol UK supplementation on energy metabolism and metabolic profile in obese humans\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3880862\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3880862\/\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTimmers, S., Konings, E., Bilet, L., Houtkooper, R.H., van de Weijer, T., Goossens, G.H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S. and Moonen-Kornips, E., 2011.  \u003cem\u003eCell metabolism\u003c\/em\u003e, \u003cem\u003e14\u003c\/em\u003e(5), pp.612-622.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":43428128751831,"sku":"10119281","price":25.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43429854675159,"sku":"101016547","price":83.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43969803288791,"sku":"101012554","price":132.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-trans-resveratrol-supplement-capsules-5192671.jpg?v=1770131598"},{"product_id":"pure-nr-sublingual-powder","title":"Pure NR Nicotinamide Riboside Supplement","description":"\u003ch2\u003e\u003cspan\u003eThe Highest Possible Potency NR Supplement for Peak NAD+ and Optimal Longevity, with 3rd Party Testing for Quality and Purity\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eOver 99% pure\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIndependently lab tested\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e100% natural and non-GMO\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eGluten-free, vegan and allergy friendly\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cul\u003e\n\u003c!-- new tab --\u003e\u003c!-- tab content --\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\n\u003cimg alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\"\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eNicotinamide riboside supplement, also known as NR supplement, is one of our most popular supplements and an alternative form of vitamin B3. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eResearch has shown that by the time we hit 50, our NAD+ levels will be half of what they were in our 20’s. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAs we age, we see significant changes in both our appearance and our overall energy levels. Our skin becomes thinner and less smooth and also begins to sag and wrinkle. At the same time easy tasks can become more difficult, with more rest being needed between them. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eAlthough this is a natural part of aging, the process itself can be slowed dramatically with the right diet and lifestyle. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eOur \u003cspan data-mce-fragment=\"1\"\u003eNicotinamide riboside\u003c\/span\u003e supplements are over 99% pure and have been independently lab tested to guarantee their quality. It’s also 100% natural, non-GMO, naturally gluten-free and vegan-friendly.  \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\"\u003eThe alternative to taking either \u003c\/span\u003eNR supplements\u003cspan style=\"font-weight: 400;\" data-mce-fragment=\"1\"\u003e or NMN is cycling between the two of them.\u003c\/span\u003e\u003cbr\u003eCycling supplements can be a smart move. With \u003ca href=\"https:\/\/longevitybox.co.uk\/products\/nmn-nr-the-ultimate-nad-combo\"\u003eNR and NMN\u003c\/a\u003e, the body produces a certain amount, depending on your age. However, there is the risk that if you introduce a higher-than-natural-level of these two precursors, the body’s metabolism may readjust and produce less of its own after a while, thus negating the benefits of a supplement. To counteract this problem, it is worth considering ‘cycling’ the two, by taking either NR for, say, a two-week period, then switching to \u003ca href=\"https:\/\/longevitybox.co.uk\/products\/ultra-pure-nmn-supplement\"\u003eNMN\u003c\/a\u003e for a two-week period, then switching back to \u003cspan data-mce-fragment=\"1\"\u003eNicotinamide riboside supplement\u003c\/span\u003e again, and so on…Another approach may be to alternate every day. Further studies are needed in this area.\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eRecommended Daily Dosage:\u003c\/h2\u003e\n\u003cp\u003eOne 300mg capsule per day\u003c\/p\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\n\u003ch3\u003eConsideration:\u003c\/h3\u003e\n\u003cp\u003eLike all vitamins, supplements, and beneficial substances, it theorised that periodic breaks from NR (one to two days off) on a weekly basis. Further studies are needed on this and there is no firm evidence to suggest whether this practice is beneficial or not, but the theory is supported by a number of knowledgeable people in the field of human biology.\u003c\/p\u003e\n\u003cbr\u003e\n\u003ch2\u003eReferences and Further Readings:\u003c\/h2\u003e\n\u003cp\u003eFor the convenience of the customers and longevity enthusiasts, listed below are several links for references. Please keep in mind that none of the sources listed below are affiliated with LongevityBox in any way.\u003cbr\u003e\u003cbr\u003e\u003ca title=\"NAD(+) Metabolism and the Control of Energy Homeostasis\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26118927\/\" target=\"_blank\"\u003e\u003cspan style=\"text-decoration: underline; color: #2b00ff;\"\u003e\u003cspan style=\"text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/26118927\/\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003cbr\u003eCantó C., Menzies K.J., Auwerx J. NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell Metab. 2015;22:31–53.\u003cbr\u003e\u003cbr\u003e\u003cspan style=\"text-decoration: underline; color: #2b00ff;\"\u003e\u003ca style=\"color: #2b00ff; text-decoration: underline;\" title=\"Nicotinamide Riboside—The Current State of Research and Therapeutic Uses\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7352172\/\" target=\"_blank\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7352172\/#B1-nutrients-12-01616\u003c\/a\u003e\u003c\/span\u003e\u003cbr\u003eMehmel M., Jovanovic N., Spitz U. Nicotinamide Riboside-The Current State of Research and Therapeutic Uses. Nutrients. 2020;12:16\u003cbr\u003e\u003cbr\u003e\u003cspan style=\"text-decoration: underline; color: #2b00ff;\"\u003e\u003ca style=\"color: #2b00ff; text-decoration: underline;\" title=\"NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29249689\/\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/29249689\/\u003c\/a\u003e\u003c\/span\u003e\u003cbr\u003eFletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. 2017 May 29\u003cbr\u003e\u003cbr\u003e\u003cspan style=\"text-decoration: underline; color: #2b00ff;\"\u003e\u003ca style=\"color: #2b00ff; text-decoration: underline;\" title=\"Nicotinamide Riboside Promotes Sir2 Silencing and Extends Lifespan\" href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(07)00390-X\" target=\"_blank\"\u003ehttps:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(07)00390-X?\u003c\/a\u003e\u003c\/span\u003e_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS009286740700390X%3Fshowall%3Dtrue\u003cbr\u003eBelenky P, Racette FG, Bogan KL, McClure JM, Smith JS, Brenner C. 2007 May 4\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":43279722578135,"sku":"101055254","price":49.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43836130590935,"sku":"101014455","price":122.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43836130656471,"sku":"101014451","price":194.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-nr-nicotinamide-riboside-supplement-8952097.png?v=1770130902"},{"product_id":"pure-calcium-alpha-ketoglutarate-powder","title":"Pure Calcium Alpha-Ketoglutarate - CA-AKG Supplement","description":"\u003cul\u003e\n\u003cli\u003eOver 99% pure\u003c\/li\u003e\n\u003cli\u003eIndependently lab tested\u003c\/li\u003e\n\u003cli\u003eGluten-free, vegan and allergy friendly\u003c\/li\u003e\n\u003cli\u003e1,000mg Ca-AKG per serving\u003c\/li\u003e\n\u003cli\u003e30 day supply\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- new tab --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- tab content --\u003e\n\u003cdiv style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhat is Ca-AKG and How Does it Work?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eAKG is known to rejuvenate cellular energy and promote cell renewal, aiding in the prevention of age-related issues and frailty. As we age, AKG production declines dramatically, with levels at age 80 dropping to just 10% of those at 40. Taking \u003cstrong\u003ecalcium AKG\u003c\/strong\u003e (Calcium Alpha-Ketoglutarate) supplements can enhance both lifespan and healthspan, helping you maintain health as you age. This powerful calcium salt comprises pure calcium combined with alpha-ketoglutarate, a key player in cellular energy metabolism and the Krebs cycle. Calcium AKG supports the process that creates ATP, which is essential for converting food into usable cellular energy. This essential supplement balances calcium's supportive role in bone health with AKG's power to facilitate cellular energy production, making it a powerhouse for promoting longevity and metabolic function \u003ca title=\"The Role of Citric Acid in Intermediate Metabolism in Animal Tissues\" rel=\"noopener\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/cr1200116\" target=\"_blank\"\u003e[1]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eThe Role of Calcium AKG in Energy Production\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCalcium AKG is deeply involved in the energy production process that fuels the body's cellular activities. The role of AKG in the citric acid cycle is foundational, as it contributes to the efficient transformation of nutrients into energy within the mitochondria. This action promotes cellular energy balance, helping to support cellular and metabolic functions that are crucial for maintaining robust health throughout the ageing process. By bolstering energy metabolism, Ca-AKG helps counteract the energy decline that often accompanies ageing \u003ca title=\"Mitochondrial function and ageing: Do mitochondria play a role in the age-related decline of cellular metabolism?\" rel=\"noopener\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1567724913002294\" target=\"_blank\"\u003e[3]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eHow Ca AKG Supports Longevity and Lifespan\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eInterest in Ca-AKG has grown significantly as research suggests that it may help to increase both lifespan and healthspan. By aiding cellular processes, Ca-AKG can promote longevity by enhancing cellular functions that typically decrease with age, such as autophagy, known as the process that clears dysfunctional cells. Ca-AKG may also positively influence DNA methylation and protein synthesis, important markers of biological age. These actions make Ca-AKG a key supplement for those seeking to decode age and promote a healthier, longer life \u003ca title=\"The metabolic regulator α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR\" rel=\"noopener\" href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(20)30452-0\" target=\"_blank\"\u003e[4]\u003c\/a\u003e\u003ca title=\"α-Ketoglutarate orchestrates cellular programaes to regulate DNA methylation\" rel=\"noopener\" href=\"https:\/\/www.nature.com\/articles\/s41467-020-17720-6\" target=\"_blank\"\u003e[5]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eExploring the Benefits of Calcium Alpha-ketoglutarate for Bone Health\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eBeyond its role in energy production, Ca-AKG is a potent ally in promoting bone health and muscle strength. The inclusion of calcium in Ca-AKG supports optimal bone density and structural integrity, which are vital as we age and our bones naturally weaken. This supplement can help support bone formation and maintenance while also contributing to improved collagen production, which is necessary for maintaining flexible, strong bones. Taking calcium AKG assists in preventing bone loss and promotes overall bone and muscle health \u003ca title=\"Effects of oral calcium supplements on femoral bone mineral density in elderly osteoporotic patients.\" rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8216437\/\" target=\"_blank\"\u003e[6]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhy Choose Ca-AKG Capsules for Healthy Ageing?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCa-AKG capsules are a convenient and highly effective supplement form that ensures consistent daily intake. The capsules contain a precise dosage of Ca-AKG, simplifying the routine of supporting your metabolic functions and cellular energy. This ease of use makes Ca-AKG capsules a practical choice for those looking to enhance their longevity and health span continuously. The capsule form allows for better absorption of pure calcium alpha-ketoglutarate, maximizing its benefits \u003ca title=\"The phosphoenolpyruvate-Krebs cycle shuttle and aging: Mechanisms of neuroprotection and cardioprotection.\" rel=\"noopener\" href=\"https:\/\/journals.sagepub.com\/doi\/abs\/10.1177\/1535370216673267\" target=\"_blank\"\u003e[7]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eCan Ca-AKG Improve Biological Age and Muscle Strength?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCa-AKG offers an innovative way to address biological age markers by supporting processes like protein synthesis and autophagy. This supplement's dual action on cellular energy and bone health can help maintain muscle strength and vitality over time. It plays a role in energy production within cells and supports bone and muscle health, helping to maintain the structural integrity and functional capacity of your body as it ages. This truly makes Ca-AKG an extensive supplement supporting long-term health and vitality \u003ca title=\"Calcium alpha-ketoglutarate enhances protein synthesis and protects against muscle wasting\" href=\"https:\/\/link.springer.com\/article\/10.1007\/s00394-015-1129-x\"\u003e[8]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhat Are Customer Reviews Saying About Ca-AKG?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCustomers consistently report positive experiences with Ca-AKG, citing notable improvements in energy levels, vitality, and overall health. Many have experienced enhanced bone strength and a stronger sense of well-being since starting the supplement. The effectiveness of Ca-AKG in reducing signs of ageing and promoting overall energy has resonated with users seeking a safe, reliable way to support their longevity.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eIs Ca-AKG Right for Your Metabolic Health?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCa-AKG is a remarkable supplement that supports various metabolic functions necessary for sustaining health as we age. It provides essential amino acids like glutamine and glutamate, which are critical for metabolic processes. By aiding in the regulation of blood sugar levels and reducing chronic inflammation, Ca-AKG helps ensure your metabolic system operates effectively. The supplement supports maintaining energy levels and metabolic efficiency, which contribute to optimal health conditions \u003ca title=\"The phosphoenolpyruvate-Krebs cycle shuttle and aging: Mechanisms of neuroprotection and cardioprotection.\" rel=\"noopener\" href=\"https:\/\/journals.sagepub.com\/doi\/abs\/10.1177\/1535370216673267\" target=\"_blank\"\u003e[9]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhy Choose Our Ca-AKG Supplement?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eSelecting the right supplement means choosing one that prioritises \u003cstrong class=\"font-serif text-lg font-medium\"\u003equality ingredients\u003c\/strong\u003e and \u003cstrong class=\"font-serif text-lg font-medium\"\u003erigorous quality control and third party testing\u003c\/strong\u003e. Every batch of our \u003cstrong\u003eCa-AKG\u003c\/strong\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003e supplement\u003c\/strong\u003e is independently tested for safety and efficacy, ensuring each dose is reliable. By using \u003cb\u003ethe finest source ingredients\u003c\/b\u003e and developed in an \u003cstrong class=\"font-serif text-lg font-medium\"\u003eFDA CGMP facility\u003c\/strong\u003e, we guarantee an \u003cstrong class=\"font-serif text-lg font-medium\"\u003eexceptional quality spermidine\u003c\/strong\u003e product that meets the highest standards.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eOur Ca-AKG is also free of additives, fillers, binders or preservatives. You will find\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003enothing but active ingredients\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ein every single Longevity Box supplement.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-1.5 mt-3 text-base\"\u003eOur world-leading 700-day purity guarantee \u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eOur 700-day purity guarantee ensures that \u003c\/span\u003e\u003cspan\u003eour products remain pure and reliable form \u003c\/span\u003e\u003cspan\u003ethe moment they arrive until you finish \u003c\/span\u003e\u003cspan\u003etaking them. Peace of mind that you truly \u003c\/span\u003e\u003cspan\u003eare extending your healthspan.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003chr class=\"my-1 border-zinc-200 dark:border-zinc-700\"\u003e\n\u003ch3 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eReferences\u003c\/h3\u003e\n\u003col class=\"my-1 list-decimal pl-6\"\u003e\n\u003cli class=\"my-1\"\u003eKrebs HA, Johnson WA. \"The Role of Citric Acid in Intermediate Metabolism in Animal Tissues.\" Enzymologia. 1937.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eChin RM, et al. \"The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.\" Nature. 2014.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003ePawlowska E, et al. \"Mitochondrial function and ageing: Do mitochondria play a role in the age-related decline of cellular metabolism?\" Mitochondrion. 2013.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eZhang J, et al. \"The metabolic regulator α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.\" Cell Reports. 2020.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eLu H, et al. \"α-Ketoglutarate orchestrates cellular programaes to regulate DNA methylation.\" Nature Communications. 2020.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eUebelhart D, et al. \"Effects of oral calcium supplements on femoral bone mineral density in elderly osteoporotic patients.\" Bone. 1993.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eGertz M, et al. \"Assessment of bioavailability of different calcium salts using serum calcium response curve methodology\" Journal of Clinical \u0026amp; Integrative Medicine. 2014.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eWu Y, et al. \"Calcium alpha-ketoglutarate enhances protein synthesis and protects against muscle wasting\" European Journal of Nutrition. 2016.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eSun K, et al. \"The phosphoenolpyruvate-Krebs cycle shuttle and aging: Mechanisms of neuroprotection and cardioprotection.\" Experimental Gerontology. 2016.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eBaziuk N, et al. \"Quality Assurance in Nutritional Supplement Production.\" Comptes Rendus Chimie. 2016.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":43685341855959,"sku":"1010188","price":24.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43685344542935,"sku":"10101772","price":73.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43873819132119,"sku":"1010101551","price":116.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/ca-akg-mega-pack-363235.jpg?v=1770130456"},{"product_id":"pure-active-sulforaphane-powder","title":"Pure Active Sulforaphane Supplement","description":"\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eActive \u003cspan\u003eS\u003c\/span\u003e\u003cspan\u003eulforaphane\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan\u003e120 x 500mg capsules\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan\u003e8.8mg of Sulforaphane per serving\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIndependently lab tested\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cbr\u003e\u003c!-- new tab --\u003e \u003c!-- tab content --\u003e\n\u003cdiv style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003ch2\u003eWhat Is Sulforaphane?\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eFresh broccoli and broccoli sprouts are two of the healthiest foods available due to their high concentrations of a category of compounds called \u003c\/span\u003e\u003cb\u003eglucosinolates\u003c\/b\u003e\u003cspan\u003e. The two most beneficial compounds are glucoraphanin and sulforaphane which have become the focus of longevity scientists in recent years with over 650 studies exploring the health benefits.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSulforaphane is an active compound found in many cruciferous vegetables like broccoli, cabbage, cauliflower, and kale. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e\u003cspan\u003eWhilst Sulforaphane is found in food, the amount is minuscule, for example, you would need to eat about more than a kilogram of broccoli to get significant amounts of sulforaphane. Sulforaphane is also a fragile compound which means that typical cooking and preparation can destroy a majority of the beneficial nutrients.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe challenge of accessing the beneficial compounds is further complicated due to Sulforaphane being found in its inactive form within food. This inactive form - glucoraphanin  - is activated into Sulforaphane only when it comes into contact with Myrosinase. These critical Myrosinase enzymes are only released when a plant is damaged, cut, chopped, or chewed, to release myrosinase and convert inactive Myrosinase into activated Sulforaphane.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecent studies show that \u003c\/span\u003e\u003ca href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/mnfr.201700980\"\u003e\u003cspan\u003eadding myrosinase derived from ground raw mustard seeds to cooked crucifers\u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e increases the bioavailability of sulforaphane by up to 4 times. This activation of glucoraphanin into sulforaphane is the focus for our Active Sulforaphane powder which is a proprietary blend of Sulforaphane, Myrosinase and black pepper.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eDosage and Guidance\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eTake with or without food. Can be mixed in a meal or drink.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cstrong\u003eIngredients per gram (1000mg)\u003c\/strong\u003e\u003c\/h3\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 56.7182%;\" data-mce-style=\"width: 56.7182%;\"\u003e \u0026gt;99% Pure Broccoli seed extract\u003c\/td\u003e\n\u003ctd style=\"width: 40.4569%;\" data-mce-style=\"width: 40.4569%;\"\u003e880mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 56.7182%; padding-left: 30px;\" data-mce-style=\"width: 56.7182%; padding-left: 30px;\"\u003e‐ Providing \u003cstrong\u003e8.8mg\u003c\/strong\u003e Sulforaphane\u003c\/td\u003e\n\u003ctd style=\"width: 40.4569%;\" data-mce-style=\"width: 40.4569%;\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 56.7182%;\" data-mce-style=\"width: 56.7182%;\"\u003eMustard seed extract\u003c\/td\u003e\n\u003ctd style=\"width: 40.4569%;\" data-mce-style=\"width: 40.4569%;\"\u003e40mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 56.7182%;\" data-mce-style=\"width: 56.7182%;\"\u003eBlack pepper\u003c\/td\u003e\n\u003ctd style=\"width: 40.4569%;\" data-mce-style=\"width: 40.4569%;\"\u003e80mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cb\u003eRecommended Daily Dosage:\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eTwo capsules per day\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cb\u003eUpper Dosage (Depending upon the age and other factors):\u003c\/b\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eFour capsules per day\u003c\/span\u003e\u003c\/p\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":44675776020695,"sku":"101018827","price":24.99,"currency_code":"GBP","in_stock":false},{"title":"3 Packs","offer_id":44983728439511,"sku":"101018828","price":73.99,"currency_code":"GBP","in_stock":false},{"title":"6 Packs","offer_id":44983760126167,"sku":"101018829","price":116.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-active-sulforaphane-supplement-9358215.jpg?v=1770130094"},{"product_id":"pure-apigenin-powder","title":"Pure Apigenin Supplement","description":"\u003cul\u003e\n\u003cli\u003eOver 99% pure Apigenin \u003c\/li\u003e\n\u003cli\u003eIndependently lab tested\u003c\/li\u003e\n\u003cli\u003e100% Natural, Non-GMO\u003c\/li\u003e\n\u003cli\u003eGluten-free, vegan and allergy-friendly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- new tab --\u003e \u003c!-- tab content --\u003e\n\u003cdiv style=\"text-align: left;\" data-mce-style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-style=\"float: none;\"\u003e\u003c\/div\u003e\n\u003cp\u003eWith 100mg per capsule, our Apigenin supplement is designed to support relaxation and promote healthy sleep. Each capsule contains 99% pure Apigenin, a naturally occurring flavone found primarily in parsley and green tea. This carefully formulated product is manufactured in the UK to the highest quality standards, ensuring its purity and safety.\u003c\/p\u003e\n\u003cp\u003eResearch indicates that Apigenin offers a range of potential benefits for sleep support and overall health. Studies suggest that this compound may positively affect cellular function, offering a natural way to enhance relaxation and promote a restful night's sleep. Apigenin has been found to have a variety of health-supporting properties, including anti-inflammatory and antioxidant effects.\u003c\/p\u003e\n\u003cp\u003eWe source our Apigenin from trusted suppliers, ensuring the highest level of purity. Each pack contains a potent dose of pure Apigenin sourced from celery seeds, with third-party testing confirming its quality and authenticity. Our commitment to quality means that you can trust our product to provide you with the highest standard of Apigenin supplementation available.\u003c\/p\u003e\n\u003cp\u003eOur Apigenin has been carefully manufactured in accordance with Good Manufacturing Practices (GMP) standards, providing you with a reliable and safe dietary supplement. We recommend consulting with a healthcare practitioner before adding any new dietary supplement to your regimen, particularly if you have any pre-existing health conditions or are taking medication.\u003c\/p\u003e\n\u003cp\u003eThe suggested dose for our Apigenin is one capsule 100mg per day, taken with food. However, individual requirements may vary, and it's important to adhere to the recommended amount per serving. It's worth noting that Apigenin can be found in grapefruit, and it's advised to avoid excessive consumption of grapefruit while using this supplement.\u003c\/p\u003e\n\u003cp\u003eApigenin is a compound that naturally occurs in certain foods, but reaching the desired levels through diet alone may be challenging. Our Apigenin offers a convenient way to ensure you're getting the right amount of this beneficial ingredient to support your sleep and overall health.\u003c\/p\u003e\n\u003cp\u003eExperience the potential benefits of Apigenin and prioritize your well-being with our high-quality Apigenin. Trust in our product's purity, safety, and research-backed formulation to support your relaxation and healthy sleep. Consult a healthcare practitioner if you have any concerns or questions about incorporating this dietary supplement into your routine. Invest in your sleep, invest in your health.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eServing Suggestions and Guidance\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eYour initial dose should be one capsules per day. This can be taken with both a meal or a drink for consumption. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for Regular Use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eThe easiest way to take our apigenin is to mix the powder into a liquid. You can then consume the liquid as part of a meal or as a standalone drink. It may be beneficial to mix Apigenin with a fat source like olive oil as this has been known to release the active compounds of fat-soluble supplements.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eReferencing and Further Readings:\u003cbr\u003e\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eFor individuals who are interested in more details and knowledge about \u003cspan\u003eApigenin\u003c\/span\u003e, here is a list of references to help you with your study. Moreover, you can watch \u003ca href=\"https:\/\/www.youtube.com\/watch?v=7FtBAr5sG8k\" title=\"Benefits of Apigenin: The Powerful Phytonutrient\" target=\"_blank\"\u003ethis\u003c\/a\u003e video by Dr Eric Berg where he provides his personal views on the benefits of \u003cspan\u003eApigenin\u003c\/span\u003e. \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6472148\/\" title=\"The Therapeutic Potential of Apigenin\" target=\"_blank\"\u003eThe Therapeutic Potential of Apigenin\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cspan\u003eSalehi B., Venditti A., Sharifi-Rad M., Kręgiel D., Sharifi-Rad J., Durazzo A., Lucarini M., Santini A., Souto E.B., Novellino E., et al. \u003cspan class=\"ref-journal\"\u003eInt. J. Mol. Sci. \u003c\/span\u003e2019.\u003cspan class=\"ref-vol\"\u003e20.\u003c\/span\u003e13\u003c\/span\u003e\u003cstrong\u003e\u003cbr\u003e\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca title=\"A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6817918\/\" target=\"_blank\"\u003eA Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eWang M., Firrman J., Liu L., Yam K. \u003cspan class=\"ref-journal\"\u003eBioMed Res. Int. \u003c\/span\u003e2019;\u003cspan class=\"ref-vol\"\u003e2019\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10942912.2016.1207188\" title=\"Health functionality of apigenin: A review\" target=\"_blank\"\u003e\u003cspan\u003eHealth functionality of apigenin: A review\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003cspan class=\"hlFld-ContribAuthor\"\u003eAli,\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"NLM_given-names\"\u003eF.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e, \u003c\/span\u003e\u003cspan class=\"hlFld-ContribAuthor\"\u003eRahul,\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"NLM_given-names\"\u003eF.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan class=\"hlFld-ContribAuthor\"\u003eNaz,\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"NLM_given-names\"\u003eS.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003eJyoti, and \u003c\/span\u003e\u003cspan class=\"hlFld-ContribAuthor\"\u003e\u003cspan class=\"NLM_given-names\"\u003eY. H.\u003c\/span\u003eSiddique. 2017; International Journal of Food Properties\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/jim.bmj.com\/content\/64\/Suppl_8\/A14.1#\" title=\"39 Studies on the antidiabetic activity of apigenin in mice with streptozotocin-induced diabetes\"\u003e\u003cspan class=\"hlFld-ContribAuthor\"\u003e39 Studies on the antidiabetic activity of apigenin in mice with streptozotocin-induced diabetes\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cstrong\u003e \u003c\/strong\u003e\n\u003cp\u003e Zhou, Yulin; Wang, Zhenzuo; Xu, Lixin; Tang, Haifeng; Wang, Di; et al. Journal of Investigative Medicine, Dec 2016 \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDisclaimers:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIt is advised to use this product at your own discretion. \u003c\/li\u003e\n\u003cli\u003eOur products are supplements and should not be considered as an alternative for a varied diet.\u003c\/li\u003e\n\u003cli\u003eConsult with your doctor before incorporating it into your daily routine.\u003c\/li\u003e\n\u003cli\u003eResearch on \u003cspan\u003eApigenin\u003c\/span\u003e is still ongoing and as more is discovered, the content on this website may get updated or changed altogether.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cbr\u003e\n\u003cdiv\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003cbr\u003e\n\u003c\/div\u003e\n\u003cbe\u003e\n\n\u003c\/be\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":43773590143191,"sku":"101014758","price":19.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43773593026775,"sku":"101014754","price":49.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43773593092311,"sku":"101014751","price":77.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-apigenin-supplement-6225822.png?v=1770130002"},{"product_id":"pure-spermidine-supplement","title":"Pure Spermidine Supplement","description":"\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003e6mg active \u003cspan\u003eSpermidine\u003c\/span\u003e\u003cspan\u003e per serving\u003c\/span\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eIndependently lab tested\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003e100% natural and non-GMO\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eNo fillers, vegan and allergy friendly\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003cspan style=\"font-weight: 400;\"\u003e60 x 350mg capsules\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"float: none;\" alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\"\u003e\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMillions of cells in your body die every second, and as we age, the body’s ability to replace these cells quickly diminishes. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAs we grow older, the body's ability to activate the process of autophagy slows down in the body. \u003c\/span\u003e\u003cspan\u003eRepaired cells are similar to young cells, and perform even better. \u003c\/span\u003eThe process of autophagy replaces old and damaged cells with healthier newer versions. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat is Spermidine and Why is it Essential?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eSpermidine is a naturally occurring\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003epolyamine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003efound in all living cells. It plays a crucial role in cellular processes, including\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eautophagy\u003c\/strong\u003e, a process that aids in cellular renewal by recycling damaged components. The\u003cspan\u003e potential \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ebenefits of spermidine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eare profound as it promotes better cell renewal, supporting overall\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ehealthspan\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand vitality. With age,\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003espermidine levels\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003etend to decline, making\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003esupplementation\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ean exciting strategy to counteract the root causes of aging.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow Does a Spermidine Supplement Work?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eOur\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003espermidine supplement\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eamplifies the natural benefits of spermidine by enhancing\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eautophagy\u003c\/strong\u003e. This process, known as what's called autophagy, helps the body efficiently remove damaged cellular components, thereby promoting\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ecell renewal\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand rejuvenation. When you think about spermidine, consider its ability to\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003esupport cognition and heart health\u003c\/strong\u003e, enhance\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eenergy levels\u003c\/strong\u003e, and facilitate improved\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003egut health\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat Are the Health Benefits of Spermidine?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ehealth benefits\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eof spermidine are diverse and significant.\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eSpermidine supplementation\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ehas been linked to supporting\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ehealthy aging\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eby boosting the body's natural ability to produce essential components for cellular health. Additionally, many notice\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003efaster growing hair and nails\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003edue to improved cellular rejuvenation processes. Enhanced\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ebrain health\u003c\/strong\u003e,\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ebetter gut health\u003c\/strong\u003e, and increased\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ecollagen synthesis\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eare also some of the\u003cspan\u003e \u003c\/span\u003e\u003cem class=\"italic\"\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003enoticeable benefits\u003c\/strong\u003e\u003c\/em\u003e\u003cspan\u003e \u003c\/span\u003eusers experience.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow is Autophagy Linked to Longevity?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eAutophagy\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eplays a pivotal role in longevity by enabling the body to\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003erecycle\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand dispose of cellular waste, a process crucial for maintaining and enhancing\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ehealthspan\u003c\/strong\u003e. By encouraging your own body's natural ability to perform\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eautophagy\u003c\/strong\u003e, our spermidine supplement aids in delaying the aging process. This contributes to a more prolonged and healthier life, embodying the essence of a\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003elongevity supplement\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow Does Wheat Germ Factor In?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eWheat germ is a powerful source of natural spermidine. Including it in our\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003espermidine supplement\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eensures a rich, natural source of this\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003epolyamine\u003c\/strong\u003e, which is essential in supporting cellular functions and longevity. By choosing food-derived spermidine, we harness nature's own method for fostering health and vitality, avoiding the need to use synthetic spermidine.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhy Choose Our Spermidine Supplement?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eSelecting the right supplement means choosing one that prioritises\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003equality ingredients\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003erigorous quality control and third party testing\u003c\/strong\u003e. Every batch of our\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003espermidine supplement\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis independently tested for safety and efficacy, ensuring each dose is reliable. By using\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003enatural spermidine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003esourced from\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003ewheat germ\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand developed in an\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eFDA CGMP facility\u003c\/strong\u003e, we guarantee an\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eexceptional quality spermidine\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eproduct that meets the highest standards.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eOur spermidine is also free of additives, fillers, binders or preservatives. You will find \u003cstrong\u003enothing but active ingredients\u003c\/strong\u003e in every single Longevity Box supplement.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-1.5 mt-3 text-base\"\u003eOur world-leading 700-day purity guarantee \u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eOur 700-day purity guarantee ensures that \u003c\/span\u003e\u003cspan\u003eour products remain pure and reliable form \u003c\/span\u003e\u003cspan\u003ethe moment they arrive until you finish \u003c\/span\u003e\u003cspan\u003etaking them. Peace of mind that you truly \u003c\/span\u003e\u003cspan\u003eare extending your healthspan.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat Makes Our Supplement Suitable for Vegans?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eOur supplements are crafted with\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003equality ingredients\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eand adhere to a strict\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003esupplement manufacturing process\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ethat avoids animal derivatives, making them\u003cspan\u003e \u003c\/span\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003esuitable for vegans\u003c\/strong\u003e. We prioritize the use of plant-derived sources ensuring the purity and integrity of every ingredient, standing apart with our commitment to ethical and sustainable practices.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-1.5 mt-3 text-base\"\u003eHuman clinical trials of Spermidine\u003c\/h2\u003e\n\u003ch3\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1756464624002706\" target=\"_blank\"\u003e\u003cspan class=\"title-text\"\u003eDietary polyamine intake lowers the risk of all-cause and cardiovascular disease-related mortality\u003c\/span\u003e\u003c\/a\u003e\u003c\/h3\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e\u003cspan class=\"font-serif text-lg font-medium\"\u003eJieun Kim , Younghwa Baek, Siwoo Lee\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e\u003cspan class=\"font-serif text-lg font-medium\"\u003eJournal of Functional Foods\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch3 class=\"mb-1.5 mt-3 text-base\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6492385\/\" target=\"_blank\"\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eSpermidine Supplementation and Cognitive Function in Older Adults\u003c\/strong\u003e\u003c\/a\u003e\u003c\/h3\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eWirth, M., Benson, G., Schwarz, C.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFrontiers in Aging Neuroscience, 2020.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003ca rel=\"noopener\" href=\"https:\/\/journal.ppcr.org\/index.php\/ppcrjournal\/article\/view\/284\" target=\"_blank\"\u003eThe Effect of Spermidine Supplementation on Cognitive Function in Adults: A Mini-Review\u003c\/a\u003e\u003c\/h3\u003e\n\u003cdiv class=\"author\"\u003eVirginia Zarama, Paulo Mattos, Kimberly Gomez\u003c\/div\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003ePrinciples and Practice of Clinical Research, 2023\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch3 class=\"mb-1.5 mt-3 text-base\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/journal.ppcr.org\/index.php\/ppcrjournal\/article\/view\/284\" target=\"_blank\"\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eImpact of Spermidine-Rich Diet on Healthspan: A Clinical Trial\u003c\/strong\u003e\u003c\/a\u003e\u003c\/h3\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eEisenberg, T., Abdellatif, M., Schroeder, S.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eNature Medicine, 2019.\u003c\/p\u003e\n\u003ch3 class=\"heading-title\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9136623\/\" target=\"_blank\"\u003eEffects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline\u003c\/a\u003e\u003c\/h3\u003e\n\u003cp\u003eClaudia Schwarz, Gloria S Benson, Nora Horn, Katharina Wurdack\u003c\/p\u003e\n\u003cp\u003eJAMA Network Open, 2022.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003cul\u003e\u003c\/ul\u003e\n\u003ch2\u003e\u003cspan\u003eSpermidine FAQ\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3\u003e\u003cspan\u003eIs Spermidine As A Supplement Safe?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSpermidine is safe as a supplement as it is one of the naturally occurring compounds in our body. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAccording to several clinical trials and scientific studies, it is entirely safe as a dietary supplement for healthy adults without having any side effects. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhen Should You Take Spermidine Supplements?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eBased on your preference, you should take spermidine supplements after any meal of the day, may it be after breakfast, lunch, or even in the evening. However, it is recommended to always take your supplement consistently at the same time during the day.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhy Should You Take Spermidine With Food?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eOne-third of spermidine is naturally produced by the cells in our body, and the rest is taken and absorbed through certain bacteria present in your digestive tract.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eTherefore, a diet balanced with a high amount of rich nutrients and spermidine sources keeps the level high.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhat Foods Are High In Spermidine?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eHigh levels of Spermidine is found in many vegetables such as potatoes, cauliflower, legumes, chickpeas (garbanzo beans), broccoli, fresh green pepper, lentils, wheat germs, rice, and rice bran. According to an estimate, people derive about 30% of all spermidine from wheat and whole grains.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSpermidine is also present in high concentrations in some fruits, such as mango. Other foods, including cheeses, amaranth grain, durian, miso, fermented soybean, or tofu (also known as natto), have high spermidine content. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMushrooms such as maitake mushrooms, oyster mushrooms, and snow mushrooms are also rich in spermidine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow Quickly Does Spermidine Work?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eCustomer feedback and anecdotal reports show that spermidine supplements can take up to 90 days to see beneficial changes in the body if taken at 10mg per day. Natural supplements take time to adjust with your body, as with any supplement or regimen.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWhere is the Best Place to Find Information on Spermidine?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eBefore taking spermidine supplements or changing your diet, you should consult with your doctor and do detailed research on spermidine and its impacts on your body. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThere are many studies and documentaries showcasing the effects of spermidine, which can help you take a healthy step in adding these longevity-increasing spermidine intake in your diet.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eWho Should Not Take Spermidine Supplements?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eSpermidine supplements are not recommended during pregnancy and lactation. According to health experts, it is not safe to take a spermidine supplement if you are pregnant or a nursing mother. It is also not suitable for children, as they are not in need of supplements such as spermidine. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eFrom What Age Should You Start Taking Spermidine Supplementation?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eYou can start taking spermidine supplements in your twenties and onwards. Although the natural autophagy process is working at its best during the early twenties, you can still begin to take spermidine supplements as it will only enhance autophagy with no side effects on your metabolism.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cspan\u003eHow Should I Feel After Taking Spermidine Supplements?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eAfter four weeks of regular spermidine supplementation, you should feel the same as you would feel during regular fasting for a few days.\u003c\/span\u003e\u003c\/p\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":43562629365975,"sku":"10101642","price":18.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43562631430359,"sku":"1010104258","price":61.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43299452125399,"sku":"101012543","price":97.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-spermidine-supplement-5814182.jpg?v=1770128954"},{"product_id":"pure-organic-ashwagandha","title":"Pure Organic Ashwagandha Supplement","description":"\u003ch2\u003e\u003cspan\u003ePure Organic Ashwagandha Capsules \u003c\/span\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eOver 99% pure\u003c\/li\u003e\n\u003cli\u003eIndependently lab tested\u003c\/li\u003e\n\u003cli\u003eNon-GMO\u003c\/li\u003e\n\u003cli\u003eGluten-free, vegan and allergy friendly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" alt=\"lab certified\" style=\"float: none;\" data-mce-style=\"float: none;\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-selected=\"1\"\u003e\u003c\/p\u003e\n\u003cp\u003eOur premium quality Organic Ashwagandha supplement is certified organic by the Soil Association and contains 1000mg per serving of pure and sustainably sourced ashwagandha root. It is a high-potency longevity supplement providing the full spectrum of active ingredients.\u003cbr\u003e\u003cbr\u003eOrganic Ashwagandha supplement is a herb native to India that has been used in Ayurvedic practice for over 3000 years.`` It is an adaptogenic herb which may help to promote a sense of calm and relaxation, as well as support the stress response, promote restful sleep and support cognitive function. It may also help to improve energy levels. Ashwagandha may work to enhance GABA signalling, which is a naturally occurring amino acid that works as a neurotransmitter in the brain, helping to produce a calming effect on the body.\u003c\/p\u003e","brand":"Longevity Box","offers":[{"title":"1 Pack","offer_id":43700016939223,"sku":"1010155447","price":17.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":43700016971991,"sku":"1010155444","price":85.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":43700017004759,"sku":"1010155448","price":136.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-organic-ashwagandha-supplement-8276271.png?v=1770128474"},{"product_id":"tmg-supplement","title":"TMG Supplement","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePotent methyl donor support for NMN\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eOver 99% Pure TMG\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eIndependently lab tested\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eGluten-free, vegan and allergy friendly\u003c\/li\u003e\n\u003cli\u003e120 x 750mg capsules\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cbr\u003e\u003cimg alt=\"lab certified\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/Lab-Banner_240x240.jpg?v=1619241906\"\u003e\u003c\/p\u003e\n\u003cdiv\u003e\n\u003cbr\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhat is TMG and Why is It Important?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eTMG, or trimethylglycine, plays significant roles in the body, mainly through its involvement in the methylation process. As a naturally occurring amino acid derivative, TMG supplies three critical methyl groups essential for methylation, a process vital for cellular repair, detoxification, and genomic stability. This process supports functions such as mood regulation and DNA synthesis \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4916962\/\" rel=\"noopener\" title=\"TMG Methylation in clinical diagnostics\" target=\"_blank\"\u003e[1]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThough found in foods like wheat bran and beets, many choose a TMG supplement to ensure adequate intake. Such supplements are beneficial for maintaining healthy blood pressure and supporting cardiovascular health by influencing homocysteine levels \u003ca href=\"https:\/\/academic.oup.com\/ajcn\/article\/76\/4\/837\/4689445\" rel=\"noopener\" title=\"Effect of betaine on plasma homocysteine concentrations in healthy volunteers\" target=\"_blank\"\u003e[2]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhy take TMG with NMN\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eWhen you increase NAD+ levels through NMN supplementation, there can be an increased demand for methyl groups due to enhanced metabolic activities. Some of the metabolites involved in these processes, like nicotinamide, need to be methylated to be removed by the body. If methylation capacity is not supported, it can potentially lead to an imbalance or depletion of methyl groups. TMG helps replenish these methyl groups, thereby supporting balanced methylation. \u003c\/span\u003e\u003cspan style=\"box-sizing: border-box; margin: 0px; padding: 0px;\"\u003eTMG can be considered an investment to ensure the \u003ca href=\"https:\/\/longevitybox.co.uk\/products\/ultra-pure-nmn-supplement\" rel=\"noopener\" target=\"_blank\"\u003eNMN\u003c\/a\u003e is created naturally in your body or maximised via supplementation.\u003c\/span\u003e\u003cspan\u003e Professor David Sinclair has spoken on his view of TMG’s role in supporting an NMN protocol and why he takes it.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhat Are the Benefits of Taking a Trimethylglycine Supplement?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eTMG supplementation offers numerous health benefits. Notably, it supports healthy homocysteine metabolism and maintains levels within a normal range, thus promoting cardiovascular health \u003ca href=\"https:\/\/academic.oup.com\/ajcn\/article\/76\/4\/837\/4689445\" rel=\"noopener\" title=\"Effect of betaine on plasma homocysteine concentrations in healthy volunteers\" target=\"_blank\"\u003e[2]\u003c\/a\u003e. TMG also enhances liver function by acting as a methyl donor in critical biochemical reactions, supporting detoxification and metabolic health.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eAdditionally, TMG supplementation is associated with increased energy production and improved mental clarity due to its role in the methylation of neurotransmitters \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23793084\/\" rel=\"noopener\" title=\"Dietary betaine and methionine: effects on plasma homocysteine concentrations in healthy adults\" target=\"_blank\"\u003e[6]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eHow Does TMG Support Cardiovascular Health?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eTMG offers valuable support for cardiovascular health through its role in converting homocysteine to methionine, an essential amino acid for protein synthesis and other significant molecules in the body. Elevated homocysteine levels have been linked to cardiovascular issues \u003ca href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/194916\" rel=\"noopener\" title=\"Homocysteine and risk of ischemic heart disease and stroke\" target=\"_blank\"\u003e[3]\u003c\/a\u003e. TMG helps lower these levels, thereby reducing the risk factors associated with cardiovascular health problems \u003ca href=\"https:\/\/academic.oup.com\/ajcn\/article\/78\/6\/1051\/4690008\" rel=\"noopener\" title=\"Homocysteine-lowering effect of oral betaine in healthy subjects: a randomized, placebo-controlled trial\" target=\"_blank\"\u003e[4]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eStudies have demonstrated that TMG can support a healthy cardiovascular function by maintaining healthy homocysteine levels \u003ca href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/01.STR.31.8.1668\" rel=\"noopener\" title=\"Clinical and nutritional correlates of plasma homocysteine in stroke patients\" target=\"_blank\"\u003e[5]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eCan TMG Improve Liver Function?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eTMG benefits liver function through its role as a methyl donor in the detoxification process. This donation boosts the liver's ability to process and eliminate toxins, crucial for maintaining overall health \u003ca href=\"https:\/\/academic.oup.com\/ajcn\/article\/76\/4\/837\/4689445\" rel=\"noopener\" title=\"Effect of betaine on plasma homocysteine concentrations in healthy volunteers\" target=\"_blank\"\u003e[2]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eAdditionally, by reducing homocysteine levels, TMG lessens the liver's metabolic load, enhancing function and promoting better metabolic clearance of waste products \u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021915005001839\" rel=\"noopener\" title=\"Dietary betaine and methionine: effects on plasma homocysteine concentrations in healthy adults\" target=\"_blank\"\u003e[7]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eHow Does TMG Impact Energy and Mental Clarity?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eTMG's impact on energy and mental clarity is significant, primarily through its enhancement of the methylation process, which supports neurotransmitter synthesis and cellular energy production. This can lead to improved mental focus and sustained energy levels \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23793084\/\" rel=\"noopener\" title=\"Dietary betaine and methionine: effects on plasma homocysteine concentrations in healthy adults\" target=\"_blank\"\u003e[6]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-1.5 mt-3 text-base\"\u003e\u003cspan\u003eWhat's the Difference Between TMG and Betaine?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e\u003cspan\u003eTrimethylglycine and betaine are two names for the same compound, a naturally occurring nutrient derived from the amino acid glycine. TMG is often referred to as betaine because it was first discovered in sugar beets, scientifically known as Beta vulgaris. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eHow to Take TMG Supplements: Recommended Dosage\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eUnderstanding the appropriate dosage is essential for effective TMG supplementation. While foods provide some betaine, supplements offer a concentrated form for specific health benefits. Research suggests dosages typically range from 500 mg to 2000 mg daily, adjusted to individual health needs \u003ca href=\"https:\/\/academic.oup.com\/ajcn\/article\/78\/6\/1051\/4690008\" rel=\"noopener\" title=\"Homocysteine-lowering effect of oral betaine in healthy subjects: a randomized, placebo-controlled trial\" target=\"_blank\"\u003e[4]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eStarting with a lower dosage and gradually increasing it under healthcare provider guidance is recommended. Monitoring blood levels ensures optimized homocysteine levels without adverse effects \u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021915005001839\" rel=\"noopener\" title=\"Dietary betaine and methionine: effects on plasma homocysteine concentrations in healthy adults\" target=\"_blank\"\u003e[7]\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eWhat Are the Potential Side Effects of TMG?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eUnderstanding potential side effects is crucial when considering any supplement. TMG is generally well-tolerated, though digestive upset or nausea might occur for some individuals when taking very high doses. As with all supplements, consultation with a healthcare provider is advised, especially when used in combination with medications to avoid interactions.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003chr class=\"my-1 border-zinc-200 dark:border-zinc-700\"\u003e\n\u003ch3 class=\"mb-2 mt-4 font-serif text-xl font-medium leading-8 md:text-2xl md:leading-[38px]\"\u003eReferences\u003c\/h3\u003e\n\u003col class=\"my-1 list-decimal pl-6\"\u003e\n\u003cli class=\"my-1\"\u003eZhou et al., \"Methylation in clinical diagnostics,\" Clin Epigenetics, 2016.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eOlthof et al., \"Effect of betaine on plasma homocysteine concentrations in healthy volunteers,\" Am J Clin Nutr, 2003.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eClarke et al., \"Homocysteine and risk of ischemic heart disease and stroke,\" JAMA, 2002.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eSteenge et al., \"Homocysteine-lowering effect of oral betaine in healthy subjects: a randomized, placebo-controlled trial,\" Am J Clin Nutr, 2003.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eCarmel et al., \"Clinical and nutritional correlates of plasma homocysteine in stroke patients,\" Stroke, 2000.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eTammen et al., \"Impact of dietary factors on the epigenome,\" Mutat Res Rev Mutat Res, 2013.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003eOlthof et al., \"Dietary betaine and methionine: effects on plasma homocysteine concentrations in healthy adults,\" Atherosclerosis, 2005.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":45373044031703,"sku":"10101753","price":19.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":45373044064471,"sku":"1010122111","price":53.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":45373020897495,"sku":"101017555","price":85.76,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/tmg-supplement-1456815.png?v=1770122561"},{"product_id":"ultra-fisetin","title":"Ultra-Fisetin Supplement","description":"\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin, a potent bioflavonoid, holds the promise of enhancing longevity and protecting against age-related cellular decline. Found naturally in strawberries and other fruits, its potential health benefits are compelling reasons to explore how this supplement can support your wellness. This article delves into the remarkable properties of fisetin and why incorporating it into your routine might be a game-changer for your health.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat is Fisetin and Where Can It Be Found?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin is a naturally occurring bioflavonoid predominantly found in fruits like strawberries. This compound is not just limited to strawberries; it's also present in apples, grapes, and other vegetables and fruits. Fisetin's promising potential health benefits make it an essential component of any anti-aging and longevity supplement.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin supplementation acts by scavenging free radicals and combating oxidative stress, elements that can significantly damage cells, leading to premature aging and various diseases. Its powerful antioxidant properties offer robust protection at the cellular level.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow Does Fisetin Promote Longevity?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe role of fisetin supplementation in promoting longevity is one of its most discussed benefits. Research suggests that fisetin may help in extending lifespan by removing senescent cells, which are cells that have stopped dividing and contribute to aging and age-related diseases. Fisetin supports cellular health and keeps cells functioning optimally.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eStudies indicate that fisetin acts as a kind of cellular clean-up agent, targeting harmful cells and facilitating the body’s natural pathways for clearing them. This process may help your body maintain healthy glucose levels and enhance overall health, contributing to a longer, healthier life.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat are the Cellular Benefits of Fisetin?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin impacts cellular health significantly. As a potent antioxidant, it reduces oxidative stress by neutralising free radicals. This is crucial because oxidative stress is a major contributor to cellular damage and aging.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe cellular benefits of fisetin also include improved cellular metabolism. Fisetin helps body's cells perform efficient metabolism, which is vital for maintaining healthy functioning and longevity. Additionally, research has shown that fisetin may support brain health by promoting autophagy, the process by which cells remove damaged components, thus supporting overall cellular vitality.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eCan Fisetin Reduce Senescent Cells?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eYes, fisetin has been shown to reduce senescent cells. These \"zombie\" cells accumulate as we age and can disrupt healthy cellular function. Fisetin acts as a senolytic, targeting and clearing out these aging cells, thereby promoting a more youthful cellular environment.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eBy clearing senescent cells, fisetin contributes to improved cellular health, potentially reducing age-related cellular decline. This senolytic activity is a cornerstone of fisetin’s potential to promote longevity.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat are the Cognitive Benefits of Fisetin?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin supports cognitive function, a benefit that adds to its appeal as a comprehensive health supplement. It may play a role in protecting brain cells and supporting cognitive function. Studies have indicated that fisetin reduces neuroinflammation and oxidative stress in the brain, promoting a healthier, more robust brain environment.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eIn addition to its neuroprotective effects, fisetin has been linked with enhanced brain function and memory. This makes it an ideal component for those looking to maintain cognitive health as they age.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow Does Fisetin Function as a Senolytic?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin is a senolytic, meaning it helps remove senescent cells from the body. These cells accumulate due to oxidative stress and contribute to aging and various age-related diseases. By acting as a senolytic, fisetin helps clear these cells, thereby supporting healthier aging and potentially extending lifespan.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eStudies indicate that fisetin acts effectively in removing these harmful cells, thereby promoting better cellular function and overall health. This ability to target and reduce senescent cells underpins its role in anti-aging and longevity.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eWhat Makes Fisetin Supplements Effective?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eFisetin supplements are effective primarily due to their high absorption rates. Longevity Box Ultra Fisetin, for instance, utilises a premium production process that ensures optimal absorption, allowing users to fully benefit from this powerful compound. Each capsule delivers a potent dose of fisetin, significantly higher than what is typically found in dietary sources alone.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe effectiveness of fisetin supplements comes from their ability to provide consistent, concentrated doses of fisetin, supporting cellular health, cognitive function, and longevity.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eAre There Any Adverse Effects of Fisetin?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eCurrently, fisetin is generally considered safe, with no significant adverse effects reported in studies. However, as with any supplement, it is advisable to consult with a healthcare professional before beginning any new supplement regimen. Fisetin supplements are formulated to be safe and are free from common allergens such as gluten and GMOs.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eSome users might experience mild digestive discomfort initially, but this typically resolves as the body adjusts to the supplement. Always follow the recommended dosages to ensure safety and effectiveness.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eHow is Fisetin Formulated for Optimal Absorption?\u003c\/h2\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThe absorption of fisetin is a critical factor in its effectiveness. Our Ultra-Fisetin, for example, is formulated with a production process that enhances bioavailability, ensuring that the body can absorb and utilise fisetin efficiently.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eThis high absorption rate is achieved by combining fisetin with other natural compounds that enhance its bioavailability, allowing users to experience its full range of health benefits.\u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"mb-3 mt-6 font-serif text-2xl font-semibold leading-[38px] md:text-3xl md:leading-[42px]\"\u003eSummary\u003c\/h2\u003e\n\u003cul class=\"my-1 list-disc pl-4\"\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003eFisetin\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eis a naturally occurring bioflavonoid with powerful antioxidant properties.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003ePromotes Longevity\u003c\/strong\u003e: Targets and removes senescent cells, supporting healthier aging.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003eCognitive Benefits\u003c\/strong\u003e: May enhance brain function and memory by reducing neuroinflammation and oxidative stress.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003eHigh Absorption\u003c\/strong\u003e: Formulations like Charava Fisetin are designed for optimal bioavailability.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003eSafe and Effective\u003c\/strong\u003e: Generally considered safe with no significant adverse effects.\u003c\/li\u003e\n\u003cli class=\"my-1\"\u003e\n\u003cstrong class=\"font-serif text-lg font-medium\"\u003eEnhanced Cellular Health\u003c\/strong\u003e: Supports metabolism, reduces oxidative stress, and promotes autophagy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"mb-1.5 mt-3 text-base\"\u003eIncorporating fisetin supplements into your daily routine could be a strategic move towards enhancing your cellular health, supporting longevity, and maintaining cognitive function as you age. With its scientifically-backed benefits, fisetin stands out as a promising addition to the anti-aging and wellness toolkit.\u003c\/p\u003e\n\u003c!----\u003e","brand":"Longevity Box","offers":[{"title":"1 Packs","offer_id":45531764981975,"sku":"101015248","price":24.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":45531765014743,"sku":"101015246","price":73.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":45531765047511,"sku":"101015250","price":116.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/ultra-fisetin-658645.jpg?v=1770122328"},{"product_id":"pure-nmnh-supplement","title":"Pure NMNH Supplement","description":"\u003ch2\u003eUltra Pure NMNH \u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eOur ultra-pure NMNH is third-party tested, offering super-high potency and 99% purity. It is manufactured in a GMP-certified facility and remains stable even under extreme heat conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eWhat Is NMNH and How Does It Work?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNMNH is a novel ingredient being studied for its ability to increase NAD+ (nicotinamide adenine dinucleotide) levels as we age. Recent research suggests that NMNH may be the most effective supplement on the market for supporting NAD+ levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNAD+ levels in our body decline with age. Supplementing with NAD may help support healthy aging, cognitive function, and immune system health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eHuman clinical trials conducted by UTHPEAK suggest that NMNH may increase NAD+ levels by THREE TIMES more than NMN and may sustain these levels for up to 20 hours, far longer than NMN. In this study, a substantial reduction in biological age was seen in the NMNH (reduced NMN) group. Participants reported a 35% increase in energy levels, experiencing noticeable fatigue relief and a significant 31% improvement in emotional wellbeing levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWhen NMNH enters the cells, it is converted into NAD+ directly, supporting mitochondrial function, which is essential for energy production. This increase in NAD+ levels not only boosts energy production but also promotes DNA repair, cognitive function, and cardiovascular health. Studies have shown that NMNH supplementation may help mitigate the effects of aging, making it a valuable supplement for those looking to improve their longevity and overall health.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/h1\u003e\n\u003ch2 dir=\"ltr\"\u003e\n\u003cspan\u003eWhy Choose Our \u003c\/span\u003e\u003cspan\u003eNMNH Supplement in the UK\u003c\/span\u003e\u003cspan\u003e?\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWe are proud to consistently produce the purest \u003c\/span\u003e\u003cspan\u003eNMNH in the UK\u003c\/span\u003e\u003cspan\u003e. It is formulated through enzymatic production, which is the cleanest and most ecological method, ensuring maximum efficacy and bioavailability whilst being kind to the planet.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eUnlike most other supplements, which often contain fillers, binders, additives, and preservatives, all our products contain only active ingredients. Manufactured in a state-of-the-art facility, our \u003c\/span\u003e\u003cspan\u003eNMNH supplement\u003c\/span\u003e\u003cspan\u003e undergoes rigorous quality testing to GMP standards and is ISO 9001:2015 quality certified.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eOur commitment to quality and purity is embodied in our world exclusive ‘700 day purity guarantee’, which ensures our products remain pure and reliable from the moment they arrive, until you finish taking them. This brings space of mind that you truly are extending your healthspan. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong class=\"font-serif text-lg font-medium\"\u003eWhy UthPeak NMNH Is the Gold Standard in NAD+ Boosters\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eLongevityBox is proud to use UthPeak NMNH in our supplements, a gold standard in NAD+ precursors, sourced from one of the most trusted and innovative manufacturers in the industry. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eUthPeak has consistently demonstrated their commitment to quality through groundbreaking research and a manufacturing process that guarantees 99% purity and super-high potency. Their clinical trials have shown that NMNH outperforms NMN by tripling NAD+ levels and maintaining these elevated levels for up to 20 hours, offering unparalleled support for cellular energy, DNA repair, and healthy aging. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBy choosing UthPeak, we ensure that every capsule we provide embodies precision, reliability, and the cutting-edge science necessary to maximise your health and longevity. \u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eHow Does NMNH Support Cellular Energy?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNMNH plays a crucial role in cellular energy production by acting as a precursor to NAD+, a coenzyme that is essential for energy metabolism. When NAD+ levels are high, mitochondrial function is optimised, leading to efficient energy production within the cells. This boost in cellular energy not only enhances overall vitality but also supports various cellular processes, including DNA repair and cellular regeneration.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSupplementing with NMNH helps to maintain high levels of NAD+ in the body, which is vital for sustaining energy production and cellular health. This can result in increased energy levels, improved cognitive function, and enhanced cardiovascular health, making NMNH an excellent supplement for those looking to support their overall well-being and longevity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e \u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eWhat Are the Proven Benefits of NMNH?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNMNH has been shown to boost NAD levels, which offers numerous potential health benefits. Some of the proven benefits of increasing NAD levels include:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eEnhanced Energy Metabolism: By boosting NAD+ levels, NMNH supports efficient energy production within the cells, leading to increased energy levels and overall vitality.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eImproved Cognitive Function: NAD+ increases have been shown to enhance brain health and cognitive function, helping to maintain mental clarity and focus as you age.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eCardiovascular Health: Boosting NAD+ supports heart health by promoting healthy blood flow and reducing oxidative stress, which can help prevent age-related cardiovascular diseases.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eHealthy Aging: Enhanced NAD levels promote healthy ageing by supporting DNA repair and cellular regeneration, helping to mitigate the effects of ageing on the body.\u003c\/span\u003e\u003cspan\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThese benefits make NMNH a valuable supplement for anyone looking to improve their health and longevity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e \u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\n\u003cspan\u003eWhy Buy \u003c\/span\u003e\u003cspan\u003eNMNH Supplements\u003c\/span\u003e\u003cspan\u003e from LongevityBox?\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWe are proud to be a UK company founded in 2021 and focused exclusively on the science of longevity. Our mission is to help everyone be younger for longer.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWith free shipping for orders over £50 and delivery in 2-3 days, our fulfilment centre in Bristol ensures your products are delivered fresh and quickly, ready to support your healthspan.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWe are committed to the best bringing you the best longevity supplements at the best prices. We're a family-run business focused on extending your healthspan, not generating bloated profits for shareholders. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/h1\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eHow to Take NMNH for Best Results?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFor optimal results, it is recommended to take NMNH daily as part of your supplement regimen. Our \u003c\/span\u003e\u003cspan\u003eNMNH supplement\u003c\/span\u003e\u003cspan\u003e comes in capsule form, making it convenient to incorporate into your daily routine. It can be taken with food or water. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe recommended dosage of NMNH can vary depending on individual needs and health goals. However, a common dosage is one 200mg capsule per day. Many people take 400mg per day, either in one serving or across two 200mg servings.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 dir=\"ltr\"\u003e\u003cspan\u003e \u003c\/span\u003e\u003c\/h1\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eHow Much NMNH Should You Take?\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe optimal dosage of NMN can vary depending on individual needs and health goals. However, a common dosage is one 200mg capsule per day. It is important to consult with a healthcare provider to determine the appropriate dosage for your specific needs.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFor those looking for a more personalised approach, NMNH supplementation can be adjusted based on factors such as age, health status, and lifestyle. By working with a healthcare provider, you can develop a supplementation plan tailored to your unique needs and goals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e \u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\n\u003cspan\u003eWhere to Buy \u003c\/span\u003e\u003cspan\u003eNMNH Supplements\u003c\/span\u003e\u003cspan\u003e?\u003c\/span\u003e\n\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIf you are looking to buy \u003c\/span\u003e\u003cspan\u003eNMNH supplements\u003c\/span\u003e\u003cspan\u003e, LongevityBox offers a high-quality products\u003c\/span\u003e\u003cspan\u003e that are backed by scientific research and rigorous quality testing. Our \u003c\/span\u003e\u003cspan\u003eNMNH capsules are\u003c\/span\u003e\u003cspan\u003e available for purchase on our website, with convenient UK delivery options to ensure that you receive your order quickly and efficiently.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWhilst we hope to serve everyone through our website, we recognise that many people prefer to use Amazon, and so you will find most of our produc\u003c\/span\u003e\u003cspan\u003ets on the UK Amazon marketplace.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eWherever you choose to buy our \u003c\/span\u003e\u003cspan\u003eNMNH supplements, you can trust that you are getting a safe, effective, and reliable product that will support your health and longevity.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\n\u003c!----\u003e\u003cbr\u003e\n\u003c\/h2\u003e\n\u003c!----\u003e","brand":"LongevityBox","offers":[{"title":"1 Pack","offer_id":54671231385980,"sku":"1010333","price":59.99,"currency_code":"GBP","in_stock":true},{"title":"3 Pack","offer_id":54671231418748,"sku":"10101444","price":159.99,"currency_code":"GBP","in_stock":true},{"title":"6 Pack","offer_id":54671231451516,"sku":"101012666","price":251.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/pure-nmnh-supplement-4331137.jpg?v=1770121902"},{"product_id":"zinc-l-carnosine","title":"Zinc L-Carnosine","description":"","brand":"Longevity Box","offers":[{"title":"1 Pack","offer_id":54822041780604,"sku":"101015442","price":26.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":54822041813372,"sku":"101015132","price":73.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":54822041846140,"sku":"101015553","price":116.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/zinc-l-carnosine-8665628.jpg?v=1770121693"},{"product_id":"alpha-gpc-supplement","title":"Alpha GPC Supplement","description":"\u003cdiv\u003e\u003cspan\u003eIntroducing Alpha GPC, a high-potency brain-boosting formula designed to support cognitive function, focus, and overall brain health. Featuring 650mg of pure Alpha GPC (L-alpha glycerylphosphorylcholine) per serving, this premium supplement provides exceptional support for those seeking to elevate their mental performance and protect long-term neurological health.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003eAlpha GPC is a highly bioavailable form of choline, a vital nutrient that plays a critical role in brain function and overall cognitive health. Unlike other choline supplements, Alpha GPC is known for its ability to cross the blood-brain barrier efficiently, delivering choline directly to the brain where it is used to produce acetylcholine—an essential neurotransmitter responsible for memory, learning, and focus. This makes Alpha GPC a standout for its ability to enhance mental clarity, improve concentration, and support sharp thinking. Additionally, its neuroprotective properties help maintain brain health over time, making it a powerful ally for healthy ageing.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003eTo further enhance its performance, our Alpha GPC only contains the pure active compound and is designed for optimal absorption and bioavailability. This ensures your body gets the maximum benefit from every dose, making it an ideal addition to both active lifestyles and long-term wellness regimens.\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv\u003e\u003cspan\u003eWhether you’re looking to excel in your daily tasks, improve your learning abilities, or support brain function as you age, Alpha GPC provides trusted, high-quality support to help you achieve your cognitive health goals. Discover why Alpha GPC is the gold standard in brain health supplements and take the next step on your journey to sharper, clearer thinking.\u003c\/span\u003e\u003c\/div\u003e","brand":"Longevity Box","offers":[{"title":"1 Pack","offer_id":55030123102588,"sku":"101015277","price":21.99,"currency_code":"GBP","in_stock":true},{"title":"3 Packs","offer_id":55030123135356,"sku":"101015278","price":54.99,"currency_code":"GBP","in_stock":true},{"title":"6 Packs","offer_id":55030123168124,"sku":"101015279","price":85.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/alpha-gpc-supplement-228407.jpg?v=1770120344"},{"product_id":"ultra-pure-methylene-blue","title":"Ultra Pure Methylene Blue","description":"\u003cp\u003eUltra Pure Methylene Blue\u003c\/p\u003e","brand":"Longevity Box","offers":[{"title":"1 Bottle","offer_id":55185964106108,"sku":"101011668","price":29.99,"currency_code":"GBP","in_stock":true},{"title":"3 Bottles","offer_id":55185964138876,"sku":"101011667","price":86.99,"currency_code":"GBP","in_stock":true},{"title":"6 Bottles","offer_id":55185964171644,"sku":"101011669","price":136.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0531\/2754\/4992\/files\/ultra-pure-methylene-blue-9082152.jpg?v=1770203468"}],"url":"https:\/\/longevitybox.co.uk\/collections\/targeted-actives.oembed","provider":"Longevity Box","version":"1.0","type":"link"}