NAD+ is the body’s most vital molecule for longevity. In fact, your brain, your muscles, your heart and every organ in your body relies on NAD+ for peak performance. And when you have optimal NAD+ levels you naturally feel more energetic, focused and youthful at any age.
Longevity Box’s NMN powder is the world’s ultimate NAD+ booster. Our high purity sublingual formulation is 500% more bioavailable. This means it’s absorbed more readily by every cell in your body. And it offers the highest possible NAD+ boost for your money.
So if you’re looking for the best way to optimise your NAD+ levels and to feel more energised, focused and vibrant each day while extending your healthspan years into the future, Longevity Box’s NMN powder is the high purity, high absorption formula that will help you do it.
The results speak for themselves
I have only been taking NMN about a month. I know there is something amazing taking place. I look forward to growing younger and younger.
Positive First Impression
Initially impressed with the science and reviews,
Now I'm impressed with the product and the immediate results!
The best way to take NMN is as a sublingual powder. I jave tried various products and can now tell by "taste" if it is the real thing. This is a good quality product and I'll probably stick with this. I can feel it working after taking.
Premium Grade Safety, Purity and Quality
Ensuring maximum levels of safety, purity and quality is everything to us. We decided early on that every supplement we develop must be supremely pure, with no unnecessary ingredients like fillers, binders or additives. Because we only want to produce supplements we’d happily take ourselves. Before launching Longevity Box, we searched globally to find the best suppliers and third party testing labs. This now ensures our products are 99% pure, and we have the purity certifications to prove it.See full report for our current batch of NMN
What is NAD+ and Why is it Vital for Longevity? NAD+ stands for nicotinamide adenine dinucleotide. And NAD+ is the body’s most important molecule for longevity. It’s NAD+ that promotes DNA repair and energy production in every human cell. And it’s NAD+ that helps your heart to pump blood, your brain cells to fire and for every organ in your body to work at its best.
But like everything else in the body, our NAD+ stores plummet with age. In fact, by age 50 your NAD+ levels are likely half what they were in your adventurous 20s. This helps explain why your energy, mental focus and feeling of youthfulness can all seem to plummet with each passing year.
Commitment to the Best Ingredients at the Best Prices
It shouldn't be only tech billionaires benefiting from the advances in longevity science. Through finding creative ways to manage costs, Longevity Box is able to provide premium grade longevity supplements at a price anyone can afford:
We buy each batch of ingredients directly from the world’s best manufacturers in large quantities.
We keep our packaging simple to minimise printing costs. We also don’t use outer boxes that just end up in landfill.
We're a family run business launched to improve the world’s healthspan, not to generate bloated profits for shareholders.
Take control of your future health
Frequently Asked Questions
Browse through some of our most commonly asked questions below.
- Why does it cost more than other supplements?
- When can I expect results?
- Is it safe to take NMN powder with my medications?
- How should I store NMN powder?
- How much should I order?
- What if it doesn't work? Can I get my money back?
Why does it cost more than other supplements?
We believe quality and purity are the most important factors when choosing a supplement, as quality determines results. We work tirelessly to find the highest quality ingredients and purity standards, which is why our NMN powder may seem more expensive than other supplements.
But when compared to other NMN powders, ours is actually great value for money. This is because our NMN powder is 99% pure and 500% more bioavailable. In other words, you gain a higher dose of NMN for your money.
When can I expect results?
Many people report an increase in energy and focus within two to four weeks. However, each person is different. And some people may require more time to achieve their desired results.
The benefits of taking NMN also build over time. In other words, the longer you take our NMN powder for the more your NAD+ levels can improve. And the bigger the benefits for your energy, brain power, heart health and all round longevity.
Is it safe to take NMN powder with my medications?
Our NMN powder is tested by third party labs in the UK for quality. This ensures maximum purity and safety for long-term use. There have been no reported unwanted side effects from our NMN powder.
However, as with any supplement, if you’re currently on medication it’s recommended to speak to your doctor before taking our NMN powder.
How should I store NMN powder?
NMN powder does degrade over time. While its degradation is slow at room temperature, degradation can be slowed even further by storing NMN powder in a fridge.
If you are planning to buy more than 3 months supply, we recommend storing the additional packets in the fridge.
How much should I order?
A small 30 gram packet is a great way to try our NMN powder out. However, the best results come from continual use over several months. For this reason, we offer a £40 discount on the 100 gram package. So for the biggest savings and biggest benefits for your longevity, we recommend investing in the 100 gram package size.
What if it doesn't work? Can I get my money back?
We want you to feel confident in giving our NMN powder a try. So we’re taking on all the risk by supplying every packet with a 30 day money back guarantee.
If within 30 days you don’t notice a boost to your energy, focus or notice no benefits at all, simply return the packet with your order information and we’ll refund your purchase to your card.
Nicotinamide Mononucleotide, also known as NMN (beta-Nicotinamide mononucleotide or β-NMN) is an entirely natural compound found in our bodies that has been scientifically synthesized in supplement form. Scientifically speaking, it is a nucleotide that has been derived from ribose and nicotinamide. Its chemical formula is C11H15N2O8P and it is a vitamin B3 Metabolite. Besides the human body, it is also found in food items such as cabbage or broccoli in traces.
It is a ribonucleotide (nucleic acid RNA’s basic structural unit) on a molecular level, with its structural molecular composition comprising:
- Nicotinamide group
- Phosphate group
In 2015, it was synthesized by scientists but the process for its manufacturing was very costly. It wasn’t until around 2018 that it was refined sufficiently and production costs were reduced enough for it to be ready for mass production.
How Does NMN Work?
NMN is the direct precursor of Nicotinamide Adenine Dinucleotide or NAD+ and plays a vital role to increase the amount of NAD+ in human cells. NAD+ is an essential coenzyme (coenzymes are catalysts needed by enzymes to complete their biochemical reactions) that is essential for a number of cellular functions. NAD+ happens to be the 2nd most abundant molecule in the human body with water being the first; without NAD+, it is present in all organisms and an important benefactor for life.
NAD+ is an oxidized form of NAD and was first discovered in 1906. Supplements containing NAD+ can’t help to boost the level of NAD+ in the human body because of the large size of the molecule that prevents it from crossing the cell membrane to enter cells.
Health expert Rhonda Patrick explains what NAD+ is, why, in her view, it is so important for aging and why it declines with age. She discusses the NAD+ boosters like nicotinamide riboside and nicotinamide mononucleotide.
Dosage and Guidelines:
It is advised to all the individuals taking it for the first time to start with a low dose and take the first dose to determine whether the product suits them or if their body reacts against it (which is highly unlikely and no such cases have been recorded).
The first dose should not exceed more than 50-60 mg and taken as per the directions indicated on the packaging. The subject should monitor themselves carefully and remain responsive to any possible adverse side effects or reactions. It is most likely that there won’t be any reaction/s, in which, case, the subject can proceed with regular dosage from the following day.
Directions for Regular Use:
The most preferred administration for NMN is ‘Sublingual Administration’ where the subject should place their daily dose under their tongue and allow it to dissolve and be absorbed. To increase the effectiveness, it is advised to divide the daily dose into smaller portions that the subject should consume throughout the day.
Alternatively, the daily recommended dose can be mixed in 100ml water and drunk. The water-mixed dose may also be sprinkled onto food and consumed (this method may lower the bio-availability of NMN).
The best method for the administration of NMN is still debated upon as some studies suggest that the oral consumption of NMN blocks or limits its delivery to tissues by the liver. On the other hand, several studies suggest the existence of a transporter gene in the small intestine from where it is carried away to cells.
The advantage of sublingual administration over forms of consumption is that it allows for direct absorption of NMN into the blood and bypasses the digestive tract, hence resulting in a much more efficient rate of absorption.
Recommended Daily Dosage:
O.5 grams per day.
Upped Dosage (Depending upon the age and other factors):
1 gram per day.
We suggest our valued clients take periodic breaks from NMN (one to two days off) on a weekly basis. though there is no evidence to suggest whether this practice is beneficial or not, it has been observed that periodic breaks can help the body to respond positively to such treatments.
- If you are on prescribed medication or have been medicating for a long term previously, then it is best to consult with your doctor before starting with NMN.
- Keep the contents in the provided packaging or an airtight glass jar. Keep away from sunlight and avoid exposure to a temperature above 24 degrees Celsius. Keep in a cool dry place and don’t expose the contents to moisture. This product can be kept in a fridge or refrigerator.
References and Further Readings:
For the convenience of the customers and enthusiasts, listed below are several links for references. Please keep in mind that none of the sources listed below are affiliated with (insert company name) in any way. For video resources, you can watch this video for Dr. David Sinclair (duration 1 hour and 12 minutes). This is also an excellent resource with a lot of useful information from Dr. Brad Stanfield (duration 30 minutes).
Cell.com. 2021. [online] Available at: <https://www.cell.com/cell-metabolism/pdf/S1550-4131(17)30670-8.pdf> [Accessed 1 February 2021].
En.wikipedia.org. 2021. Nicotinamide mononucleotide. [online] Available at: <https://en.wikipedia.org/wiki/Nicotinamide_mononucleotide> [Accessed 1 February 2021].
Li, J., Bonkowski, M.S., Moniot, S., Zhang, D., Hubbard, B.P., Ling, A.J., Rajman, L.A., Qin, B., Lou, Z., Gorbunova, V. and Aravind, L., 2017. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. Science, 355(6331), pp.1312-1317.
Gomes, A.P., Price, N.L., Ling, A.J., Moslehi, J.J., Montgomery, M.K., Rajman, L., White, J.P., Teodoro, J.S., Wrann, C.D., Hubbard, B.P. and Mercken, E.M., 2013. Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell, 155(7), pp.1624-1638.
Das, A., Huang, G.X., Bonkowski, M.S., Longchamp, A., Li, C., Schultz, M.B., Kim, L.J., Osborne, B., Joshi, S., Lu, Y. and Treviño-Villarreal, J.H., 2018. Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging. Cell, 173(1), pp.74-89.
Abc.net.au. 2021. Scientists reverse ageing process in mice. [online] Available at: <https://www.abc.net.au/news/2014-11-04/scientists-reverse-ageing-process-in-mice/5865714> [Accessed 1 February 2021].
En.wikipedia.org. 2021. Nicotinamide adenine dinucleotide. [online] Available at: <https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide> [Accessed 1 February 2021].
Imai, S.I. and Guarente, L., 2014. NAD+ and sirtuins in aging and disease. Trends in cell biology, 24(8), pp.464-471.
Srivastava, S., 2016. Emerging therapeutic roles for NAD+ metabolism in mitochondrial and age-related disorders. Clinical and Translational Medicine, 5(1), pp.1-11.
Chini, E.N., 2009. CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions. Current pharmaceutical design, 15(1), pp.57-63.
North, B.J., Rosenberg, M.A., Jeganathan, K.B., Hafner, A.V., Michan, S., Dai, J., Baker, D.J., Cen, Y., Wu, L.E., Sauve, A.A. and Van Deursen, J.M., 2014. SIRT 2 induces the checkpoint kinase BubR1 to increase lifespan. The EMBO journal, 33(13), pp.1438-1453.
Elhassan, Y.S., Philp, A.A. and Lavery, G.G., 2017. Targeting NAD+ in metabolic disease: new insights into an old molecule. Journal of the Endocrine Society, 1(7), pp.816-835.
Fang, E.F., Scheibye-Knudsen, M., Chua, K.F., Mattson, M.P., Croteau, D.L. and Bohr, V.A., 2016. Nuclear DNA damage signalling to mitochondria in ageing. Nature reviews Molecular cell biology, 17(5), pp.308-321.
- NMN powder is provided and supplied in re-sealable food-graded/food-safe pouches/bags that are transparent on one side. This transparent-sided pouch/bag is provided in another bag/pouch that prevents any moisture or light from entering the transparent-sided pouch. It is advised to keep the clear-sided bad/pouch in this protective bag/pouch at all times. Additionally, there is a scooping spoon provided that carries 250 mg NMN powder when leveled.
- It is advised to use this product at your own discretion. NMN is a fairly recently discovered product and long-term effects on humans are yet to be determined.
- This is just a supplement and should not be considered as an alternative for a varied diet.
- Consult with your doctor before incorporating it into your daily routine.
- The research pertaining to NMN is still ongoing and new data is surfacing on a daily basis. this means that data on our website is subject to change.
At Longevity Box we are committed to sourcing the highest purity longevity supplements on the market. Our products are pharmaceutical grade and independently verified for quality and purity by renowned third party test laboratories.
We work with well established suppliers that have regular factory inspections and are certified with CGMP and ISO to ensure the highest standards are consistently met. We have third party independent laboratories test every batch of product that is produced and display on our website the latest tests for the batch that is currently in stock.
Please see below the latest third party independent test certificates for our current batch of Longevity supplements.
Independent laboratory testing is critical to ensure that the product is at least 99% pure and contains no dangerous levels of heavy metals or micro-organisms. If an online retailer is not providing test results then there is no certainty that there products is pure or even the product that they claim it to be and whether it’s safe for human consumption. Establishing purity and authenticity is critical when consuming small molecule longevity supplements like NMN. It is clear that the market has many websites selling impure or fake NMN.
Every batch of Longevity Box supplements is independently verified to have a purity of at least 99%, with no dangerous levels of heavy metals or micro-organisms. You can find the latest certifications for each product here:
NMN purity certificates
Resveratrol purity certificates
NR purity certificates
Ca-AKG purity certificates
Apigenin purity certificates
We are committed to your long term health and will always ensure our products are of the highest purity and quality.
Money Back Guarantee
We want you to be delighted with every purchase from us. In the unfortunate and unlikely event that you’re not delighted we offer a 30-day Money Back Satisfaction Guarantee.
With our Money Back Satisfaction Guarantee we are committed to:
- Issuing a full refund for all unopened products
- Issuing a refund of 50% of the purchase price for returned products that have at least 50% of the product remaining for products up to the value of £300
Return Procedures: Please send an email to CustomerServices@LongevityBox.co.uk with your complete name, address, phone # and your order # . Once we have received this email and confirmed that your order is eligible to be returned, we will provide you with a return authorisation number and a return address to send the goods.
Once we have received your return package we will inspect for quality to ensure the product you return is genuine. This authenticity inspection may take up to 30 days. Upon confirmation of authenticity, you will receive your refund and email confirming that your return request has been accepted. You will either be credited back to your Card, or PayPal. Please allow 5 working days for us to process the refund and up to 5 working days to receive your refund by card.
Unfortunately it is not possible for us to refund any delivery charges incurred when sending the product back to us.